Mechanisms of tumor immune microenvironment remodeling in current cancer therapies and the research progress.
- Author:
Yuanzhen YANG
1
;
Zhaoyang ZHANG
1
;
Shiyu MIAO
1
;
Jiaqi WANG
1
;
Shanshan LU
1
;
Yu LUO
1
;
Feifei GAO
1
;
Jiayue ZHAO
1
;
Yiru WANG
2
;
Zhifang XU
3
Author Information
1. Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, College of Acupuncture-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
2. College of Acupuncture-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
3. Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, College of Acupuncture-moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193; Tianjin Key Laboratory of Modern Traditional Chinese Medicine Theory Innovation and Translation, Tianjin 301617, China. *Corresponding author, E-mail: xuzhifangmsn@hotmail.com.
- Publication Type:English Abstract
- MeSH:
Tumor Microenvironment/immunology*;
Humans;
Neoplasms/therapy*;
Immunotherapy/methods*;
Animals
- From:
Chinese Journal of Cellular and Molecular Immunology
2025;41(4):372-377
- CountryChina
- Language:Chinese
-
Abstract:
The cellular and molecular components of the tumor immune microenvironment (TIME) and their information exchange processes significantly influence the trends of anti-tumor immunity. In recent years, numerous studies have begun to evaluate TIME in the context of previous cancer treatment strategies. This review will systematically summarize the compositional characteristics of TIME and, based on this foundation, explore the impact of current cancer therapies on the remodeling of TIME, aiming to provide new insights for the development of innovative immune combination therapies that can convert TIME into an anti-tumor profile.
