Advances in the study of exosomes derived from mesenchymal stem cells in the treatment of pulmonary diseases.
- Author:
Tao MA
1
;
Linzhi YUE
1
;
Yumei DAI
1
;
Wenya DU
1
;
Lixian WU
2
,
3
Author Information
1. Department of Microbiology and Immunology, School of Basic Medicine, Dali University, Dali 671000, China.
2. Department of Microbiology and Immunology, School of Basic Medicine, Dali University, Dali 671000, China. *Corresponding author, E-mail: w_lixian@
3. com.
- Publication Type:English Abstract
- MeSH:
Exosomes/transplantation*;
Humans;
Mesenchymal Stem Cells/metabolism*;
Lung Diseases/therapy*;
Animals
- From:
Chinese Journal of Cellular and Molecular Immunology
2025;41(3):278-282
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary diseases, as a prevalent category of respiratory system disorders, have become a significant global public health concern. The increasing incidence of these diseases, caused by environmental pollution and occupational hazards, poses a substantial threat to human health and the overall quality of life. Mesenchymal stem cells (MSCs) are known for their remarkable immunomodulatory, anti-bacterial, and anti-apoptotic capabilities. Exosomes derived from MSCs, carrying a diverse array of proteins, lipids, nucleic acids, and other bio-active molecules, have demonstrated considerable therapeutic potential in treating pulmonary diseases, and have come to the forefront of medical research. This review summarized the therapeutic role of exosomes derived from various sources of mesenchymal stem cells in the context of pulmonary diseases, aiming to provide a robust foundation for their clinical application in diagnosis and treatment.