Research progresses on the mechanism of macrophages in tendon bone healing.

Liang WANG; Yinshuan DENG; Tao QU; Chaoming DA; Yunfei HE; Rui LIU; Weimin NIU; Weishun YAN; Zhen CHEN; Shuo LI; Zhiyun YANG; Binbin GUO; Xueqian LAI

Return

Research progresses on the mechanism of macrophages in tendon bone healing.

Author: Liang WANG ¹ ; Yinshuan DENG ^{2
,

3} ; Tao QU ¹ ; Chaoming DA ¹ ; Yunfei HE ¹ ; Rui LIU ¹ ; Weimin NIU ¹ ; Weishun YAN ¹ ; Zhen CHEN ¹ ; Shuo LI ¹ ; Zhiyun YANG ¹ ; Binbin GUO ¹ ; Xueqian LAI ⁴
Author Information

1. Orthopedics Department, Gansu Provincial Central Hospital, Lanzhou 730070, China.
2. Orthopedics Department, Gansu Provincial Central Hospital, Lanzhou 730070, China. *Corresponding author, E-mail: kefandeng@
3. com.
4. Department 2 of Children's Emergency Center of Gansu Provincial Central Hospital, Lanzhou 730070, China.
Publication Type:English Abstract
MeSH: Humans; Macrophages/metabolism*; Wound Healing; Animals; Tendons/physiology*; Bone and Bones/injuries*; Tendon Injuries
From: Chinese Journal of Cellular and Molecular Immunology 2025;41(2):183-187
CountryChina
Language:Chinese
Abstract: The connection between tendons and bones is called the tendon bone connection. With the continuous improvement of national sports awareness, excessive exercises and the related intensity are prone to damage the tendon bone connection. Tendon bone healing is a complex repair and healing process involving multiple factors, and good tendon bone healing is a prerequisite for its physiological function. The complexity of tendon bone structure also poses great challenges to the repair of tendon bone injuries. In recent years, researches have found that stem cells, growth factors, macrophages, and other factors are closely related to the healing process of tendon bone injuries, among which macrophages play an important role in the healing process. The authors reviewed relevant research literature in recent years and summarized the role of macrophages in tendon bone healing, in order to provide new ideas and directions for treatment strategies to promote tendon bone healing.