Advances in the role and mechanism of tumor-associated neutrophils in gastric cancer.
- Author:
Yinyin YUAN
1
;
Fangfang LI
1
;
Dongfang LI
2
,
3
Author Information
1. Hunan University of Chinese Medicine, School of integrated Chinese and Western, Changsha 410208, China.
2. Hunan University of Chinese Medicine, School of integrated Chinese and Western, Changsha 410208; Hunan Cancer Hospital, The department of Traditional Chinese Medicine/Integrative Oncology, Changsha 410013, China. *Corresponding author, E-mail: kekou3190@
3. com.
- Publication Type:English Abstract
- MeSH:
Humans;
Stomach Neoplasms/therapy*;
Neutrophils/pathology*;
Animals
- From:
Chinese Journal of Cellular and Molecular Immunology
2025;41(2):172-177
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer (GC) is a highly prevalent malignant tumor of the digestive system, with high incidences and mortality rates worldwide, posing a serious threat to human health. Studies have shown that tumor-associated neutrophils (TAN) are closely related to adverse biological behaviors of GC, such as initiation, invasion and metastasis, immune evasion, and resistance to treatment, playing a pivotal role in the pathological progression of GC. This article aims to summarize the role of neutrophils in the onset and development of GC and explore their potential applications in GC treatment by reviewing relevant literature in recent years, in order to provide reference for clinicians and basic research.
