Clinical efficacy of separation surgery in treating spinal metastases accompanied by neurological symptoms.
10.12200/j.issn.1003-0034.20240153
- Author:
Qiang WANG
1
;
Min-Hao LU
1
;
Xing-Wu WANG
1
;
Ming FANG
1
;
Wu-Liang YU
1
;
Jian-Meng LU
1
Author Information
1. Department of Spinal Surgery, the First Affiliated Hospital of Ningbo University, Ningbo 315000, Zhejiang, China.
- Publication Type:Journal Article
- Keywords:
Neurological symptom;
Separation surgery;
Spinal metastases
- MeSH:
Humans;
Female;
Male;
Middle Aged;
Aged;
Spinal Neoplasms/complications*;
Adult;
Aged, 80 and over;
Quality of Life
- From:
China Journal of Orthopaedics and Traumatology
2025;38(2):157-163
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the safety and effectiveness of separation surgery in patients with neurological symptoms of spinal metastases.
METHODS:From January 2020 to December 2022, 14 patients with neurological symptoms of spinal metastases underwent separation surgery, including 7 males and 7 females, aged from 30 to 76 years old with an average of (61.57±12.16) years old. In comparison with eleven patients underwent conservative treatment during the same period, including 6 males and 5 femals, aged from 46 to 88 years old with an average of (66.55±12.32) years old. The changes in visual analogue scale (VAS), Frankel grades, Karnofsky scores, and quality of life score (QOL) before and after treatment were compared between two groups.
RESULTS:Fourteen patients in the separation surgery group underwent surgery successfully, with surgery time of (218.57±50.00) minutes and intraoperative blood loss of (864.29±332.97) ml, 2 patients developed delayed hematoma and recovered well finally after emergency surgery, the follow-up time was 3 to 36 months, after separation surgery, the pain was significantly relieved, and neurological function recovered well in the patients. Three months after treatment, the VAS in the separation surgery group (1.43±0.76) scores was significantly lower than that in the conservative treatment group (8.64±0.51) scores (P<0.05);and the Frankel grades, Karnofsky scores, and QOL scores in the separation surgery group were significantly better than those in the conservative treatment group(P<0.05).
CONCLUSION:For patients with obvious neurological symptoms of spinal metastases, separation surgery not only can rapidly relieve nerve compression but also carry relatively low surgical risks, and improve the quality of life of patients.
