Research progress in etiology and prevention of bone cement implantation syndrome.
10.7507/1002-1892.202410068
- Author:
Guangtao HAN
1
;
Qin WANG
1
;
Shuo SUN
1
;
Pengde KANG
1
Author Information
1. Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China.
- Publication Type:English Abstract
- Keywords:
Bone cement implantation syndrome;
etiology;
joint arthroplasty;
prevention
- MeSH:
Humans;
Bone Cements/adverse effects*;
Postoperative Complications/etiology*;
Arthroplasty, Replacement, Hip/adverse effects*;
Risk Factors;
Syndrome;
Methylmethacrylate/adverse effects*
- From:
Chinese Journal of Reparative and Reconstructive Surgery
2025;39(2):237-242
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To introduce the etiology and prevention of bone cement implantation syndrome (BCIS).
METHODS:The literature about BCIS at home and abroad in recent years was extensively reviewed, and the incidence, clinical manifestations, etiology, and prevention of BCIS were summarized and analyzed.
RESULTS:The clinical manifestations of BCIS are diverse. The etiology of BCIS is not completely clarified, and it may be related to circulating methyl methacrylate-mediated model, embolus-mediated model, histamine release and hypersensitivity response, complement activation and multimodal model. BCIS prevention begins with the identification of high-risk patients in preoperative evaluation and communication between surgeon and anesthesiologist about the choice of implant type, surgical procedure, and technique to minimize the risk of cardiovascular complications in high-risk patients with multiple or severe risk factors or comorbidities. Preoperative assessment and optimization of a patient's cardiovascular reserve is also critical to prevent BCIS.
CONCLUSION:BCIS is a possible complication after hip joint arthroplasty, and its pathogenesis needs to be further research in order to provide new ideas for prevention and treatment.
