Research progress on combined transcranial electromagnetic stimulation in clinical application in brain diseases.
10.7507/1001-5515.202410055
- Author:
Yujia WEI
1
;
Tingyu WANG
1
;
Chunfang WANG
2
;
Ying ZHANG
2
;
Guizhi XU
1
Author Information
1. State Key Laboratory of Intelligent Power Distribution Equipment and System, School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, P. R. China.
2. Tianjin Union Medical Center, The First Affiliated Hospital of Nankai University, Tianjin 300121, P. R. China.
- Publication Type:English Abstract
- Keywords:
Brain diseases;
Neuromodulation;
Transcranial electrical stimulation;
Transcranial electromagnetic combined stimulation;
Transcranial magnetic stimulation
- MeSH:
Humans;
Transcranial Magnetic Stimulation/methods*;
Transcranial Direct Current Stimulation/methods*;
Brain Diseases/therapy*
- From:
Journal of Biomedical Engineering
2025;42(4):847-856
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the ongoing development of transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS) has demonstrated significant potential in the treatment and rehabilitation of various brain diseases. In particular, the combined application of TES and TMS has shown considerable clinical value due to their potential synergistic effects. This paper first systematically reviews the mechanisms underlying TES and TMS, highlighting their respective advantages and limitations. Subsequently, the potential mechanisms of transcranial electromagnetic combined stimulation are explored, with a particular focus on three combined stimulation protocols: Repetitive TMS (rTMS) with transcranial direct current stimulation (tDCS), rTMS with transcranial alternating current stimulation (tACS), and theta burst TMS (TBS) with tACS, as well as their clinical applications in brain diseases. Finally, the paper analyzes the key challenges in transcranial electromagnetic combined stimulation research and outlines its future development directions. The aim of this paper is to provide a reference for the optimization and application of transcranial electromagnetic combined stimulation schemes in the treatment and rehabilitation of brain diseases.