A study on the predictive model of porous hyperelastic properties of human alveolar bone based on computed tomography imaging.
10.7507/1001-5515.202408014
- Author:
Bin WU
1
;
Mingna LI
1
;
Fan YANG
2
;
Le YUAN
1
;
Yi LU
1
;
Di JIANG
1
;
Yang YI
1
;
Bin YAN
2
Author Information
1. School of Mechanical and Electronic Engineering, Nanjing Forestry University, Nanjing 210037, P. R. China.
2. Department of Orthodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing 210029, P. R. China.
- Publication Type:Journal Article
- Keywords:
Alveolar bone;
Bone mineral density;
Finite element simulation;
Hyperelasticity;
Predictive model
- MeSH:
Humans;
Tomography, X-Ray Computed/methods*;
Porosity;
Alveolar Process/physiology*;
Bone Density;
Computer Simulation;
Elasticity;
X-Ray Microtomography;
Stress, Mechanical;
Finite Element Analysis;
Models, Biological
- From:
Journal of Biomedical Engineering
2025;42(2):359-365
- CountryChina
- Language:Chinese
-
Abstract:
Alveolar bone reconstruction simulation is an effective means for quantifying orthodontics, but currently, it is not possible to directly obtain human alveolar bone material models for simulation. This study introduces a prediction method for the equivalent shear modulus of three-dimensional random porous materials, integrating the first-order Ogden hyperelastic model to construct a computed tomography (CT) based porous hyperelastic Ogden model (CT-PHO) for human alveolar bone. Model parameters are derived by combining results from micro-CT, nanoindentation experiments, and uniaxial compression tests. Compared to previous predictive models, the CT-PHO model shows a lower root mean square error (RMSE) under all bone density conditions. Simulation results using the CT-PHO model parameters in uniaxial compression experiments demonstrate more accurate prediction of the mechanical behavior of alveolar bone under compression. Further prediction and validation with different individual human alveolar bone samples yield accurate results, confirming the generality of the CT-PHO model. The study suggests that the CT-PHO model proposed in this paper can estimate the material properties of human alveolar bone and may eventually be used for bone reconstruction simulations to guide clinical treatment.
