Research progress on point-of-care testing of blood biochemical indexes based on microfluidic technology.
10.7507/1001-5515.202406061
- Author:
Huaqing ZHANG
1
;
Canjie HU
2
;
Pengjia QI
2
;
Zhanlu YU
2
;
Wei CHEN
3
;
Jijun TONG
2
Author Information
1. Department of Clinical Medical Engineering, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, P. R. China.
2. College of Information Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, P. R. China.
3. Hangzhou Baiyi Health Technology Co., LTD., Hangzhou 311217, P. R. China.
- Publication Type:English Abstract
- Keywords:
Blood biochemical index;
Microfluidic;
Real-time detection;
Self-sampling
- MeSH:
Humans;
Point-of-Care Testing;
Lactic Acid/blood*;
Microfluidic Analytical Techniques/methods*;
Blood Glucose/analysis*;
Point-of-Care Systems;
Blood Chemical Analysis/instrumentation*;
Uric Acid/blood*;
Cholesterol/blood*;
Dopamine/blood*;
Microfluidics/methods*
- From:
Journal of Biomedical Engineering
2025;42(1):205-211
- CountryChina
- Language:Chinese
-
Abstract:
Blood biochemical indicators are an important basis for the diagnosis and treatment by doctors. The performance of related instruments, the qualification of operators, the storage method and time of blood samples and other factors will affect the accuracy of test results. However, it is difficult to meet the clinical needs of rapid detection and early screening of diseases with currently available methods. Point-of-care testing (POCT) is a new diagnostic technology with the characteristics of instant, portability, accuracy and efficiency. Microfluidic chips can provide an ideal experimental reaction platform for POCT. This paper summarizes the existing detection methods for common biochemical indicators such as blood glucose, lactic acid, uric acid, dopamine and cholesterol, and focuses on the application status of POCT based on microfluidic technology in blood biochemistry. It also summarizes the advantages and challenges of existing methods and prospects for development. The purpose of this paper is to provide relevant basis for breaking through the technical barriers of microfluidic and POCT product development in China.
