"Kidney deficiency-vessel impairment" as core pathogenesis of panvascular diseases: theoretical and clinical perspectives.
10.19540/j.cnki.cjcmm.20250516.701
- Author:
Jie WANG
1
;
Jun HU
1
;
Jun LI
1
;
Zhen-Peng ZHANG
1
;
Chao LIU
1
;
Cong CHEN
1
Author Information
1. Guang'anmen Hospital, China Academy of Chinese Medical Sciences Beijing 100053, China.
- Publication Type:English Abstract
- Keywords:
kidney deficiency-vessel impairment;
kidney-tonifying therapy;
panvascular diseases;
pharmacological mechanism
- MeSH:
Humans;
Drugs, Chinese Herbal/therapeutic use*;
Kidney/blood supply*;
Vascular Diseases/physiopathology*;
Animals;
Kidney Diseases/physiopathology*
- From:
China Journal of Chinese Materia Medica
2025;50(13):3513-3521
- CountryChina
- Language:Chinese
-
Abstract:
Panvascular disease is a complex systemic disorder. Research by our team has established "kidney deficiency-vascular impairment" as its core pathogenesis. Consequently, we developed a three-tiered progressive prevention and treatment strategy: early prevention phase: focuses on tonifying the kidney and reducing turbidity; mid-term control phase: focuses on tonifying the kidney and stabilizing plaque; late recovery phase: focuses on tonifying the kidney and unblocking collaterals. This targeted therapeutic protocol effectively alleviates clinical symptoms, improves biochemical markers, enhances treatment efficacy, and achieves comprehensive management throughout the disease course. This article systematically elaborates on the concept of "kidney deficiency-vascular impairment" in panvascular disease, summarizes the mechanisms of kidney-tonifying Chinese herbal medicines, aiming to provide a beneficial reference for the whole-course management of panvascular diseases.
