Research progress on pharmacological effects and mechanism of α-asarone and β-asarone in Acori Tatarinowii Rhizoma.
10.19540/j.cnki.cjcmm.20250211.602
- Author:
Hao WANG
1
;
Lei GAO
1
;
Jin-Lian ZHANG
1
;
Ling-Yun ZHONG
1
;
Shu-Han JIN
1
;
Xiao-Yan CHEN
1
;
Wen ZHANG
1
;
Jia-Wen WEN
1
Author Information
1. Jiangxi University of Chinese Medicine Nanchang 330004, China.
- Publication Type:English Abstract
- Keywords:
Acori Tatarinowii Rhizoma;
antitumour;
cardiovascular system diseases;
central nervous system diseases;
α-asarone;
β-asarone
- MeSH:
Allylbenzene Derivatives;
Acorus/chemistry*;
Anisoles/chemistry*;
Rhizome/chemistry*;
Drugs, Chinese Herbal/chemistry*;
Humans;
Animals
- From:
China Journal of Chinese Materia Medica
2025;50(9):2305-2316
- CountryChina
- Language:Chinese
-
Abstract:
Acori Tatarinowii Rhizoma is the dried rhizome of Acorus tatarinowii in the family of Tennantiaceae, which has the efficacy of opening up the orifices and expelling phlegm, awakening the mind and wisdom, and resolving dampness and opening up the stomach. Modern studies have shown that volatile oil is the main active ingredient of Acori Tatarinowii Rhizoma, and α-asarone and β-asarone have been proved to be the active ingredients in the volatile oil of Acori Tatarinowii Rhizoma, with pharmacological effects such as anti-Alzheimer's disease, antiepileptic, anti-Parkinson's disease, antidepressant, anticerebral ischemia/reperfusion injury, anti-thrombosis, lipid-lowering, and antitumor. By summarising and outlining the pharmacological effects of α-asarone and β-asarone and elucidating the possible mechanisms of their pharmacological effects, we can provide theoretical basis for the further research and clinical application of Acori Tatarinowii Rhizoma.
