Review of chemical constituents, pharmacological effects, and quality control status of Eucommiae Cortex and prediction of its Q-markers.
10.19540/j.cnki.cjcmm.20241112.201
- Author:
Meng-Fan PENG
1
;
Bao-Song LIU
2
;
Pei-Pei YAN
3
;
Cai-Xia LI
4
;
Xiao-Fang ZHANG
3
;
Yi ZHENG
3
;
Ya-Gang SONG
5
;
Tong LIU
6
;
Lei YANG
3
;
Ming-San MIAO
5
Author Information
1. School of Medicine, Huanghuai University Zhumadian 463000, China NMPA Key Laboratory for Safety Research and Evaluation of Traditional Chinese Medicine, Henan University of Chinese Medicine Zhengzhou 450046, China.
2. Department of Pharmacy, Zhumadian Traditional Chinese Medicine Hospital Zhumadian 463000, China.
3. School of Medicine, Huanghuai University Zhumadian 463000, China.
4. Department of Pharmacy, the First Affiliated Hospital of Xinxiang Medical University Xinxiang 453100, China.
5. NMPA Key Laboratory for Safety Research and Evaluation of Traditional Chinese Medicine, Henan University of Chinese Medicine Zhengzhou 450046, China.
6. Department of Traditional Chinese Medicine Management, Henan Cancer Hospital Zhengzhou 450046, China.
- Publication Type:English Abstract
- Keywords:
Eucommiae Cortex;
chemical constituent;
pharmacological effect;
quality control;
quality marker
- MeSH:
Eucommiaceae/chemistry*;
Drugs, Chinese Herbal/pharmacology*;
Quality Control;
Humans;
Animals
- From:
China Journal of Chinese Materia Medica
2025;50(4):946-958
- CountryChina
- Language:Chinese
-
Abstract:
Eucommiae Cortex, the dried bark of Eucommia ulmoides( Eucommiaceae), has both medicinal and edible values.Modern research has shown that Eucommiae Cortex contains various components such as flavonoids, lignans, iridoids, phenolic acids,terpenoids, and steroids, which have anti-osteoporosis, antioxidant, anti-inflammatory, blood glucose-lowering, and gastrointestinal tract-protecting effects. Eucommiae Cortex has applications in multiple fields such as healthcare, industry, and animal husbandry,demonstrating broad development prospects. This article reviews the chemical constituents, pharmacological effects, and quality control status of Eucommiae Cortex. Furthermore, according to the concept of quality marker(Q-marker), this article predicts the Q-markers of Eucommiae Cortex from traditional medicinal properties, traditional medicinal effects, new medicinal effects, measurability of chemical components, compatibility, harvesting periods, and geographical origins. The components such as pinoresinol diglucoside,chlorogenic acid, caffeic acid, quercetin, baicalein, baicalin, olivil, coniferyl ferulate, and kaempferol can be used as Q-markers for Eucommiae Cortex, which provide reference for establishing a systematic quality control system for Eucommiae Cortex.
