Research progress in chemical constituents and pharmacological activities of Abelmoschi Corolla and prediction of its quality markers.
10.19540/j.cnki.cjcmm.20241126.201
- Author:
Shi-Han GUAN
1
;
Chang LIU
1
;
Xiao-Tong YAN
1
;
Jin-Wei HAN
1
;
Feng-Ting YIN
1
;
Hui SUN
1
;
Guang-Li YAN
1
;
Ling KONG
1
;
Ying HAN
1
;
Xi-Jun WANG
1
Author Information
1. State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Chinmedomics Research Center of National Administration of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine Harbin 150040, China.
- Publication Type:English Abstract
- Keywords:
Abelmoschi Corolla;
chemical constituent;
mechanism of action;
pharmacological activity;
quality marker
- MeSH:
Abelmoschus/chemistry*;
Drugs, Chinese Herbal/pharmacology*;
Flowers/chemistry*;
Humans;
Animals;
Quality Control;
Flavonoids/chemistry*
- From:
China Journal of Chinese Materia Medica
2025;50(4):908-921
- CountryChina
- Language:Chinese
-
Abstract:
Abelmoschi Corolla, the dried corolla of Abelmoschus manihot, has anti-inflammatory, antioxidant, and anti-fibrosis activities. Its chemical constituents mainly include flavonoids, organic acids, steroids, and polysaccharides. This study reviewed the research progress in the chemical constituents and pharmacological activities of Abelmoschi Corolla in recent 20 years. According to the concept of quality marker(Q-marker), the Q-markers of Abelmoschi Corolla were predicted from plant phylogeny, chemical constituent specificity, traditional efficacy, chemical constituent measurability, and absorbed constituents. The primary Q-markers for Abelmoschi Corolla were anticipated to include quercetin-3'-O-β-D-glucopyranoside, gossypetin-8-O-β-D-glucuronide, isoquercetin, myricetin,quercetin, and hyperoside, with the aim of providing reference data for improving the quality evaluation system of Abelmoschi Corolla.
