Research progress in alkaloids and their pharmacological effects from plants of Rutaceae.

Author: Qiu-Juan CHEN ¹ ; Xiao-Wei SU ¹ ; Hui-Ting ZHANG ¹ ; Rui LI ¹ ; Yu-Ling LIU ¹ ; Hua-Feng ZHOU ¹ ; Jian SU ¹ ; Li-Ni HUO ¹
Author Information

1. College of Pharmacy, Guangxi University of Chinese Medicine Nanning 530200, China.
Publication Type:English Abstract
Keywords: Rutaceae; alkaloids; anti-inflammation; antitumor; pharmacological effects
MeSH: Alkaloids/chemistry*; Humans; Rutaceae/chemistry*; Animals; Drugs, Chinese Herbal/chemistry*; Anti-Inflammatory Agents/chemistry*
From: China Journal of Chinese Materia Medica 2024;49(22):6030-6047
CountryChina
Language:Chinese
Abstract: The plants of Rutaceae, with wide distribution in China, have a long history of medicinal use. They contain a wide variety of alkaloids, which include isoquinolines, quinolines, acridones, carbazoles, and indoles. Pharmacological studies have shown that most of these alkaloids have antitumor, anti-inflammatory, antiviral, antidiabetic and other activities. This article summarized 378 alkaloids isolated from plants of Rutaceae and their pharmacological effects, aiming to lay a basis for future drug development and sustainable utilization of plant resources.