The role of selenoproteins in adipose tissue and obesity.
- Author:
Yun-Fei ZHAO
1
;
Yu-Hang SUN
1
;
Tai-Hua JIN
1
;
Yue LIU
1
;
Yang-Di CHEN
1
;
Wan XU
1
;
Qian GAO
1
Author Information
- Publication Type:English Abstract
- MeSH: Selenoproteins/metabolism*; Adipose Tissue/physiology*; Obesity/metabolism*; Humans; Animals; Selenium
- From: Acta Physiologica Sinica 2025;77(5):939-955
- CountryChina
- Language:Chinese
- Abstract: Selenoproteins, as the active form of selenium, play an important role in various physiological and pathological processes, such as anti-oxidation, anti-tumor, immune response, metabolic regulation, reproduction and aging. Although the expression level of selenoproteins in adipose tissue is significantly influenced by dietary selenium intake, it is closely related to the homeostasis of adipose tissue. In this review, we summarized the role of selenoproteins in the physiological function of adipose tissue and the pathogenesis of obesity in recent years, in order to provide a rationale for developing potential therapeutic agents for the treatment of obesity and related metabolic diseases.
