Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection for 31 cases of allergic rhinitis.
10.13703/j.0255-2930.20241202-k0007
- Author:
Dong HAN
1
;
Chunsheng YIN
1
;
Yuping YANG
1
Author Information
1. Department of Acupuncture-Moxibustion and Tuina, Weifang Hospital of TCM, Weifang 261000, Shandong Province, China.
- Publication Type:Clinical Trial
- Keywords:
allergic rhinitis;
immunoregulation;
inflammatory factors;
medical ozone;
wheat-grained sized cone moxibustion
- MeSH:
Humans;
Female;
Male;
Moxibustion;
Adult;
Ozone/administration & dosage*;
Middle Aged;
Young Adult;
Acupuncture Points;
Adolescent;
Combined Modality Therapy;
Treatment Outcome;
Immunoglobulin E/blood*;
Rhinitis, Allergic/immunology*;
Interleukin-4/immunology*
- From:
Chinese Acupuncture & Moxibustion
2025;45(12):1739-1742
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy of combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone penetrating injection for allergic rhinitis (AR) and its effect on inflammation-related indexes.
METHODS:Thirty-one patients with persistent AR were enrolled. The patients received medical ozone injection at bilateral Yingxiang (LI20)-to-Shangyingxiang (EX-HN8), and wheat-grained sized cone moxibustion at Dazhui (GV14), twice a week (with a 3-day interval) for 4 consecutive weeks. The total nasal symptoms score (TNSS), total non-nasal symptom score (TNNSS), rhinoconjunctivitis quality of life questionnaire (RQLQ), and rhinitis control assessment test (RCAT) scores were evaluated before treatment, after treatment, and at the 8-week follow-up. Levels of eosinophil (EOS) count, immunoglobulin E (IgE), interleukin (IL)-4, IL-6, and IL-17 were measured before and after treatment. Clinical efficacy was evaluated after treatment, and the recurrence rate was assessed at follow-up.
RESULTS:Compared with those before treatment, the TNSS, TNNSS, and RQLQ scores were decreased (P<0.05), while the RCAT score was increased (P<0.05) after treatment and at follow-up. There were no statistically significant differences in above indexes between the post-treatment and follow-up (P>0.05). After treatment, the whole blood EOS count and serum levels of IgE, IL-4, IL-6, and IL-17 were decreased compared with those before treatment (P<0.05). After treatment, 17 cases were markedly effective, 12 cases were effective, and 2 cases were ineffective, resulting in a total effective rate of 93.5%. At follow-up, 2 cases relapsed, and the recurrence rate was 6.9%.
CONCLUSION:Combination therapy of wheat-grained sized cone moxibustion and point-to-point needle insertion with medical ozone injection can improve AR symptoms, reduce the recurrence rate, and enhance the quality of life. The mechanism may be associated with the regulation of immune-related indexes.
