Jiuci renmai therapy combined with bladder function training for post-stroke neurogenic bladder: a randomized controlled trial.
10.13703/j.0255-2930.20250302-0001
- Author:
Qiang HUANG
1
;
Chunning LI
1
;
Hongyu XIE
2
;
Baoguo WANG
3
;
Zhenya WANG
4
;
Yi CAO
3
Author Information
1. Graduate School, Anhui University of CM, Hefei 230012, China.
2. First Affiliated Hospital of Anhui University of CM.
3. Department of Encephalopathy, Second Affiliated Hospital of Anhui University of CM, Hefei
4. Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei
- Publication Type:English Abstract
- Keywords:
bladder function training;
jiuci renmai;
post-stroke neurogenic bladder;
randomized controlled trial (RCT);
urodynamics;
voiding
- MeSH:
Humans;
Female;
Male;
Middle Aged;
Urinary Bladder, Neurogenic/etiology*;
Urinary Bladder/physiopathology*;
Adult;
Aged;
Stroke/complications*;
Acupuncture Therapy;
Acupuncture Points;
Treatment Outcome;
Combined Modality Therapy;
Moxibustion
- From:
Chinese Acupuncture & Moxibustion
2025;45(10):1427-1433
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical effect and safety of Jiuci renmai therapy (moxibustion and acupuncture on the conception vessel) combined with bladder function training in treatment of post-stroke neurogenic bladder (PSNB).
METHODS:Sixty patients with PSNB were randomly divided into an observation group and a control group, 30 cases in each group. On the basis of conventional treatment with western medication, bladder function training was delivered in the control group, once a day for 4 weeks. In the observation group, Jiuci renmai therapy was supplemented besides the regimen as the control group. The main acupoints were Guanyuan (CV4), Zhongji (CV3), Qihai (CV6) and Qugu (CV2); and the supplementary acupoints were Henggu (KI11), Zhongwan (CV12), Xiawan (CV10) and Shuifen (CV9). Warm needling and moxibustion were operated, once every other day, for 4 weeks. Separately, before treatment and in 2 and 4 weeks of treatment, the urodynamic parameters were detected in the two groups, including maximal urine flow rate (Qmax), maximal detrusor pressure (PdetQmax), residual urine volume (RUV), maximal bladder capacity in the filling phase (MCC), and maximal intravesical pressure in the voiding phase (Pvesmax); the voiding parameters (the average daily number of micturition, urinary leakage episodes, and single voiding volume) were recorded; neurogenic bladder symptom score (NBSS), lower urinary tract symptom score (LUTS) and the score of quality of life scale for incontinence of urine (I-QoL) were evaluated, as well as the clinical effect and safety in the two groups.
RESULTS:In 2 and 4 weeks of treatment, Qmax, PdetQmax, MCC, Pvesmax, and average daily single voiding volume were increased compared with the levels before treatment in each group (P<0.05), and the above indexes in the observation group were higher than those of the control group (P<0.05). RUV, the average daily number of micturition, urinary leakage episode, NBSS and LUTS scores of the two groups were reduced in comparison with those before treatment (P<0.05 ), and these indexes in the observation group were lower than those of the control group (P<0.05). In 4 weeks of treatment, the average urinary leakage episode was reduced largely in comparison with the control group (P<0.05); and the improvement in RUV for the patients with retention of urine in the observation group was superior to the control group (P<0.05). In 4 weeks of treatment, the score of each dimension in I-QoL and the total score were elevated compared with those before treatment in the two groups (P<0.05), and the scores in the observation were higher when compared with the control group (P<0.05). The total effective rate in the observation group was 90.0% (27/30) which was higher than 70.0% (21/30) of the control group (P<0.05). The incidence of adverse reactions was 3.3% (1/30) in the observation group, which was not significantly different from that in the control group [10.0% (3/30), P>0.05].
CONCLUSION:The combination of Jiuci renmai therapy and bladder function training can effectively alleviate clinical symptoms, recover bladder voiding function, and improve the quality of life in the patients with PSNB, presenting the favorable safety profile in treatment.
