Heat-sensitive moxibustion robot for improving depressive state in methamphetamine addicts during withdrawal period: a randomized controlled trial.
10.13703/j.0255-2930.20250402-k0001
- Author:
Yuexia JIANG
1
;
Haiyan LI
2
;
Wei HE
3
;
Jing ZHOU
4
;
Chunliang ZOU
5
;
Dingyi XIE
6
;
Rixin CHEN
6
Author Information
1. School of Clinical Medicine, Jiangxi University of CM, Nanchang 330006, China.
2. Heat-Sensitive Moxibustion Translational Medicine Research Center, Jiangxi University of CM.
3. Drug Detoxification Administration of Jiangxi Province.
4. Jiangxi Provincial Compulsory Isolation Drug Rehabilitation Center.
5. Jiangxi Women's Compulsory Isolation Drug Rehabilitation Center.
6. Department of Acupuncture and Moxibustion, Affiliated Hospital of Jiangxi University of CM, Nanchang
- Publication Type:English Abstract
- Keywords:
depression;
deqi;
heat-sensitive moxibustion;
methamphetamine addiction;
randomized controlled trial (RCT)
- MeSH:
Humans;
Moxibustion/methods*;
Male;
Adult;
Female;
Methamphetamine/adverse effects*;
Depression/therapy*;
Middle Aged;
Robotics;
Young Adult;
Amphetamine-Related Disorders/psychology*;
Acupuncture Points;
Substance Withdrawal Syndrome/psychology*
- From:
Chinese Acupuncture & Moxibustion
2025;45(8):1061-1067
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy of heat-sensitive moxibustion robot for improving the depressive state of methamphetamine addicts during withdrawal period.
METHODS:A total of 60 patients with methamphetamine addiction accompanied with depressive state were randomly divided into an observation group (40 cases, 4 cases dropped out) and a control group (20 cases, 2 cases dropped out). The control group received routine health education and addiction treatment in compulsory isolation drug rehabilitation center. On the basis of the treatment in the control group, in the observation group, the heat-sensitive moxibustion robot was used to locate sensitive points at the Shenque (CV8) and Danzhong (CV17), and dual-point sparrow-pecking moxibustion was delivered for 60 min per session. The moxibustion therapy was performed 4 times in the 1st week, 3 times in the 2nd and 3rd weeks respectively, and 2 times in the 4th week, for 12 times totally. The scores of Hamilton depression scale (HAMD), self-rating depression scale (SDS), visual analogue scale (VAS) for drug craving, Hamilton anxiety scale (HAMA), self-rating anxiety scale (SAS), and Pittsburgh sleep quality index (PSQI) were observed before treatment, at the end of the 2nd and 4th weeks of treatment, and 4 weeks after the treatment completion (follow-up) in the two groups.
RESULTS:At each time point after treatment, in the observation group, the HAMD, VAS, HAMA and PSQI scores were decreased compared with those before treatment (P<0.01, P<0.001); at the end of the 4th week of treatment and in follow-up, the SDS and SAS scores were decreased compared with those before treatment (P<0.001, P<0.01). Compared before treatment, there were no significant differences in the above scores at each time point after treatment in the control group (P>0.05). In the observation group, at each time point after treatment, the HAMD and VAS scores were lower than those in the control group (P<0.01, P<0.001, P<0.05); at the end of the 4th week of treatment and in follow-up, the SDS and HAMA scores were lower than those in the control group (P<0.05, P<0.001); at the end of the 4th week of treatment, the PSQI score was lower than that in the control group (P<0.01).
CONCLUSION:Heat-sensitive moxibustion robot effectively improves depression, anxiety and sleep quality, and reduces drug craving in methamphetamine addicts during withdrawal period.
