Electroacupuncture at "four points of sacral region" for mild-to-moderate benign prostatic hyperplasia with lower urinary tract symptoms: a randomized controlled trial.
10.13703/j.0255-2930.20240322-k0003
- Author:
Jie ZHOU
1
;
Mengyi ZHENG
2
;
Shan CHEN
3
;
Yiying ZHAO
1
;
Ruijie MA
2
Author Information
1. Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310005, China.
2. Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou
3. First Affiliated Hospital of Zhejiang Chinese Medical University.
- Publication Type:English Abstract
- Keywords:
benign prostatic hyperplasia;
electroacupuncture;
four points of sacral region;
lower urinary tract symptoms;
mild-to-moderate;
randomized controlled trial (RCT)
- MeSH:
Humans;
Male;
Electroacupuncture;
Prostatic Hyperplasia/complications*;
Aged;
Middle Aged;
Lower Urinary Tract Symptoms/physiopathology*;
Acupuncture Points;
Treatment Outcome;
Quality of Life
- From:
Chinese Acupuncture & Moxibustion
2025;45(5):627-632
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy of electroacupuncture (EA) at "four points of sacral region" for mild-to-moderate benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS).
METHODS:A total of 58 patients with BPH/LUTS were randomly divided into a sacral four-point EA group (29 cases, 1 case dropped out) and a conventional EA group (29 cases, 1 case dropped out). EA was applied at bilateral points 0.5 cun lateral to the sacrococcygeal joint and Huiyang (BL35) in the sacral four-point EA group; and was applied at Guanyuan (CV4), Zhongji (CV3), Qugu (CV2) and bilateral Shuidao (ST28), Sanyinjiao (SP6), Zusanli (ST36) in the conventional EA group. Both groups received continuous wave, 2 Hz in frequency, 30 min a time, once every other day, 3 times a week for 4 weeks. Before treatment, after 2 and 4 weeks of treatment, and in follow-up of 1 month after treatment completion, the international prostate symptom score (IPSS), the overactive bladder symptom score (OABSS), the quality of life (QOL) score were observed; before and after treatment, the prostate volume (PV) was measured by abdominal ultrasound; and the clinical efficacy was evaluated after treatment in the two groups.
RESULTS:Compared before treatment, the scores of IPSS, OABSS and QOL were decreased after 4 weeks of treatment and in follow-up in both groups (P<0.01, P<0.05). In the sacral four-point EA group, the scores of IPSS and QOL after 4 weeks of treatment and in follow-up were lower than those in the conventional EA group (P<0.05, P<0.01), and the OABSS score in follow-up was lower than that in the conventional EA group (P<0.05). After 4 weeks of treatment and in follow-up, the reductions of IPSS and OABSS scores compared before treatment in the sacral four-point EA group were larger than those in the conventional EA group (P<0.01, P<0.05); After 2, 4 weeks of treatment and in follow-up, the reductions of QOL score compared before treatment in the sacral four-point EA group were larger than those in the conventional EA group (P<0.01). No significant difference in PV was observed after treatment between the two groups (P>0.05). The total effective rate was 75.0% (21/28) in the sacral four-point EA group, which was higher than 39.3% (11/28) in the conventional EA group (P<0.01).
CONCLUSION:EA at "four points of sacral region" can effectively improve the LUTS, overactive bladder symptom and quality of life in patients with mild-to-moderate BPH, and has good short-term and long-term efficacy, although it can not reduce prostate volume.
