Effect of needle cauterization on vitiligo with deficiency cold and blood stasis: a randomized controlled trial.
10.13703/j.0255-2930.20240531-k0004
- Author:
Honghong DU
1
;
Xiang LIU
1
;
Beibei WU
1
;
Tongtong LI
1
;
Nan LIU
1
Author Information
1. Department of Dermatology, Hebei Hospital of TCM, Shijiazhuang 050011, China.
- Publication Type:English Abstract
- Keywords:
308 nm excimer light irradiation;
ironing with Chinese medicine;
needle cauterization;
randomized controlled trial (RCT);
vitiligo, deficiency cold and blood stasis
- MeSH:
Humans;
Vitiligo/physiopathology*;
Male;
Female;
Adult;
Young Adult;
Middle Aged;
Adolescent;
Interleukin-6/blood*;
Interleukin-17/blood*;
Cautery;
Acupuncture Therapy/instrumentation*;
Needles;
Cold Temperature;
Treatment Outcome
- From:
Chinese Acupuncture & Moxibustion
2025;45(3):327-330
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical effect of needle cauterization on vitiligo with deficiency cold and blood stasis.
METHODS:A total of 62 patients of vitiligo with deficiency cold and blood stasis were randomly divided into an observation group and a control group, 31 cases each group.On the basis of 308 nm excimer light irradiation combined with ironing with Chinese medicine, the control group was treated with tacrolimus ointment for external use, twice a day; the observation group was treated with needle cauterization at vitiligo spots, once a week.Both groups were treated for 10 weeks. Before and after treatment, the area of vitiligo spot, TCM syndrome score, serum levels of inflammatory indexes (interleukin[IL]-6 and IL-17) were observed in the two groups, and the clinical effect was evaluated.
RESULTS:After treatment, the areas of vitiligo spot, TCM syndrome scores and serum levels of IL-6, IL-17 were decreased compared with those before treatment in both groups (P<0.05), and the above indexes in the observation group were lower than those in the control group (P<0.05). The total effective rate in the observation group was 93.5% (29/31), which was higher than 77.4% (24/31) in the control group (P<0.05).
CONCLUSION:Needle cauterization could reduce the areas of vitiligo spot in patients of vitiligo with deficiency cold and blood stasis, improve the clinical symptoms, its mechanism may be related to the reduction of serum levels of inflammatory indexes.
