Research progress in molecular mechanism of acupuncture for diabetes mellitus.
10.13703/j.0255-2930.20240604-0003
- Author:
Kaiting HE
1
;
Qinhong ZHANG
2
;
Jinhuan YUE
2
;
Tong PU
3
;
Hao CHI
4
;
Qiaoyun WU
5
;
Songhe JIANG
5
;
Guanhu YANG
6
Author Information
1. School of Acupuncture-Moxibustion and Tuina, Shandong University of CM, Jinan 250355, China.
2. Shenzhen Frontier Chinese Medicine Research Co. Ltd.
3. School of Acupuncture-Moxibustion and Tuina, Beijing University of CM.
4. Clinical Medicine School, Southwest Medical University.
5. International Institute of Acupuncture and Rehabilitation, Wenzhou Medical University.
6. Department of Specialty Medicine, Ohio University, Ohio 43055, USA.
- Publication Type:English Abstract
- Keywords:
acupuncture;
diabetes mellitus;
molecular biological mechanism;
research progress
- MeSH:
Humans;
Acupuncture Therapy;
Diabetes Mellitus/genetics*;
Animals;
Insulin/metabolism*;
Signal Transduction
- From:
Chinese Acupuncture & Moxibustion
2024;44(11):1357-1362
- CountryChina
- Language:Chinese
-
Abstract:
This paper discusses the mechanism of acupuncture for diabetes mellitus from the perspective of molecular biology, aiming to reveal the potential rules of restoring the balance in the body and fighting against diabetes mellitus (DM). By searching the basic research literature of acupuncture treatment for DM, it is found that the molecular biological mechanism of acupuncture treatment for DM is closely related to the regulation of insulin signaling pathway, the modulation of inflammatory response, the protection and regeneration of islet β-cells, fat metabolism and energy balance. It points out that there are few studies of acupuncture on the type 1 diabetes mellitus and the large-scale randomized controlled trials, as well as the studies on the upstream regulation mechanism, the specific cellular molecules and the interaction mechanism of various molecules. It needs to deepen the multi-level, multi-target and multi-dimensional exploration on the molecular biological mechanism of acupuncture for diabetes mellitus.
