Current status of functional testing for upper gastrointestinal disorders: state-of-the-art review.
10.4103/singaporemedj.SMJ-2025-106
- Author:
Andrew Xia Huang TAN
1
;
Alex Yu Sen SOH
2
;
Jonathan Ziyang KUANG
3
;
Kewin Tien Ho SIAH
4
;
Andrew Ming Liang ONG
5
;
Daphne ANG
1
Author Information
1. Department of Gastroenterology and Hepatology, Changi General Hospital, Singapore.
2. Division of Gastroenterology and Hepatology, Department of Medicine, Alexandra Hospital, Singapore.
3. Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore.
4. Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore.
5. Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore.
- Publication Type:Review
- Keywords:
Functional gastrointestinal disorders;
neurogastroenterology;
upper
- MeSH:
Humans;
Gastrointestinal Diseases/physiopathology*;
Upper Gastrointestinal Tract/physiopathology*;
Gastrointestinal Motility;
Endoscopy, Gastrointestinal
- From:Singapore medical journal
2025;66(8):431-438
- CountrySingapore
- Language:English
-
Abstract:
Neurogastroenterology and motility disorders of the upper gastrointestinal (GI) tract represent a complex and heterogeneous group of conditions that involve the interaction between the GI tract and the central nervous system. They constitute a significant number of outpatient gastroenterology visits, resulting in a high healthcare burden. These disorders often occur in the absence of identifiable structural causes on routine endoscopy and radiological imaging. A more targeted approach in the assessment of functional GI disorders is increasingly being integrated into routine clinical practice, given the recent advancements in technology and physiologic testing. When used in the appropriate clinical context, these tests not only elucidate the physiological basis for the patient's symptoms, but also prevent inappropriate treatment and repeated investigations. This review aims to summarise the advances in clinically available diagnostic tools for the evaluation of upper GI functional disorders.
