Association of vaccine knowledge and vaccine literacy with vaccine hesitancy among parents of preschool children
10.16835/j.cnki.1000-9817.2025346
- VernacularTitle:学龄前儿童父母疫苗知识和疫苗素养与疫苗犹豫的关联
- Author:
DONG Shuwen, WU Yuqian, ZHU Liwan, ZENG Yuexian, XIANG Xinrong, GAN Jianzhe, REN Li
1
Author Information
1. Department of Public Health Data Management, Guangzhou Center for Disease Control and Prevention/Guangzhou Health Supervision Institute, Guangzhou 510440, Guangdong Province, China
- Publication Type:Journal Article
- Keywords:
Vaccines;
Knowledge;
Health education;
Attitude;
Child,preschool
- From:
Chinese Journal of School Health
2025;46(11):1580-1583
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the mediating role of vaccine literacy between vaccine knowledge and vaccine hesitancy and the moderating role of parental education level, so as to provide references for adjusting vaccination strategies.
Methods:From May to December 2024, a stratified random sampling method was used to select 10 community hospitals in Guiyang and Zunyi City, Guizhou Province. A total of 1 401 parents of children aged 0-6 years were surveyed regarding their socio demographic characteristics, vaccine knowledge, vaccine literacy, and vaccine hesitancy levels. Data were analyzed using common method bias tests, Spearman correlation analysis, mediation and moderation effects tests.
Results:The mean score for vaccine knowledge, vaccine literacy and vaccine hesitancy were (2.96±1.11, 14.25±2.64, 39.12±4.93) among the 1 401 participants. Mediating effect analysis showed that both parental vaccine knowledge ( β =1.28, 95% CI =1.08-1.49) and vaccine literacy ( β =0.75, 95% CI =0.66-0.84) positively predicted vaccine hesitancy (both P <0.01). Meanwhile, vaccine literacy accounted for 28.1% of the total effect of mediation between knowledge and vaccine hesitancy. In the moderated effects analysis, education level positively predicted vaccine literacy ( β =0.40, 95% CI =0.24-0.57), and education level moderated the pathway of vaccine knowledge on vaccine hesitancy ( β = 0.28 , 95% CI =0.05-0.52) (both P <0.01).
Conclusions:Vaccine literacy partially mediates the relationship between vaccine knowledge and vaccine hesitancy. Parental education level positively moderates the prediction of vaccine knowledge on vaccine hesitancy score.
