Clinical Symptoms of Schizophrenia Assessed Using the Positive and Negative Syndrome Scale (PANSS)
- VernacularTitle:Шизофренийн эмнэлзүйн шинжүүдийг позитив ба негатив хам шинжийн үнэлгээ (PANSS)-ний сорилоор үнэлсэн нь
- Author:
Oyunchimeg N
1
;
2
;
Nasantsengel L
2
;
Sarantuya J
1
Author Information
1. Department of Molecular Biology and Genetics, School of Biomedicine, MNUMS
2. National Center of Mental Health Mongolia
- Publication Type:Journal Article
- Keywords:
Chronic psychotic disorder, Delusion, Affect, Hostility, Avolition
- From:
Mongolian Journal of Health Sciences
2025;89(5):146-149
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Schizophrenia is a severe psychiatric disorder of endogenous origin, characterized by the coexistence of
prominent positive and negative symptoms and a chronic course. It typically begins during adolescence or early adulthood,
leading to disturbances in cognition, thought processes, and emotional regulation, which subsequently result in loss
of daily functioning and impairment in social adaptation.
Aim:The aim of this study was to evaluate the clinical manifestations of schizophrenia using the Positive and Negative
Syndrome Scale (PANSS) and to determine the severity levels of positive, negative, and general psychopathological
symptoms.
Materials and Methods:A cross-sectional study was conducted at the National Center for Mental Health between December
2016 and December 2019. A total of 102 patients with schizophrenia, aged 20 to 66 years, who were under active
outpatient follow-up, were included in the study. Clinical symptoms were assessed using the PANSS.
Results:Of the 102 participants, 51% (n=129) were female, with a mean age of 40±12 years. The distribution of positive,
negative, and general psychopathological symptoms showed that 21–24% were in the mild to moderate range. Notably,
23% of patients presented with severe negative symptoms, such as blunted affect, social withdrawal, and reduced motivation,
indicating that these features are particularly prominent in advanced stages of schizophrenia. Positive symptoms
were found to be mild to moderate in 15–24% of patients, suggesting that hallucinations and delusions are more pronounced
during the early course of the illness but tend to decline as the disease progresses. General psychopathological
symptoms were observed in 12–22% of patients, remaining relatively stable across all severity levels.
Conclusion:In the early stages of schizophrenia, positive symptoms predominate, whereas in the advanced stages negative
symptoms become more prominent. General psychopathological symptoms appear consistently across all levels of
severity. These findings highlight the importance of evaluating both positive and negative dimensions when assessing the
clinical course of schizophrenia.
- Full text:2025121012014176449Шизофренийн эмнэлзүйн шинжүүдийг позитив ба негатив хам шинжийн үнэлгээ (PANSS)-.pdf
