Association Between Metabolic Alterations and Anthropometric Parameters in Women with Polycystic Ovary Syndrome
- VernacularTitle:Өндгөвч уйланхайжих хам шинжтэй эмэгтэйчүүдийн бодисын солилцооны өөрчлөлт ба антропометрийн зарим үзүүлэлтийг уялдуулан судалсан дүн
- Author:
Khulan A
1
;
Oyuntugs B
2
;
Bolorchimeg B
3
Author Information
1. Department of Obstetrics and Gynecology, School of Medicine, MNUMS
2. Department of Endocrinology, School of Medicine, MNUMS
3. Wonder Women’s Hospital
- Publication Type:Journal Article
- Keywords:
Ovary, Anthrophometr, polycystic, Uric acid, Neck circumference, BMI, Metabolism
- From:
Mongolian Journal of Health Sciences
2025;89(5):64-67
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Polycystic ovary syndrome (PCOS) is characterized by menstrual irregularities, hormonal imbalance,
clinical or biochemical hyperandrogenism, and the presence of multiple ovarian follicles. It is one of the major causes of
infertility, endometrial carcinoma, and pregnancy-related complications. PCOS is not limited to the reproductive system;
it is a chronic disorder associated with metabolic abnormalities and increased cardiovascular risk, which can negatively
affect women’s long-term quality of life.In recent years, growing attention has been given to the metabolic alterations seen
in women with PCOS-particularly hyperuricemia-and to the emerging role of novel anthropometric indicators such as
neck circumference. Given the limited data on these parameters among Mongolian women with PCOS, this study aimed
to investigate the relationship between serum uric acid levels and selected anthropometric measurements.
Aim:To examine the association between serum uric acid concentration and selected anthropometric parameters in
women with polycystic ovary syndrome.
Materials and Methods:This analytical cross-sectional study was conducted in a clinical setting and included 120
women aged 15–35 years. Participants completed a structured questionnaire that collected information on age, menstrual
cycle characteristics, and medication use. Anthropometric measurements-including height, weight, neck, waist, and
hip circumference—were recorded. PCOS was diagnosed based on the Rotterdam criteria. Serum uric acid levels were
determined through biochemical testing. Statistical analyses were performed using the t-test and Pearson correlation test.
Results:Of the 120 women enrolled, 45.8% (n=55) were diagnosed with PCOS according to the Rotterdam criteria, while
54.2% (n=65) were classified as controls. The mean neck circumference was 36.2±2.5 cm in the PCOS group and 31.5±1.8
cm in the control group (p<0.001). The mean waist circumference was 88.4±7.9 cm in the PCOS group and 75.8±6.7 cm in
the control group (p<0.001). The mean hip circumference was 103.5±6.5 cm among women with PCOS and 94.7±5.5 cm
in the control group (p<0.01). The waist-to-hip ratio was significantly higher in the PCOS group (0.85±0.07) compared to
controls (0.80±0.05, p<0.05). Among women with PCOS, the mean serum uric acid concentration was 476±8.5 µmol/L,
which-although not exceeding the upper reference limit for women (400 µmol/L) was slightly higher than the average
value in healthy individuals.
Conclusion:Compared with healthy controls, women with PCOS demonstrated significantly higher anthropometric
indices. Although serum uric acid did not surpass the reference maximum, elevated mean levels indicate a potential
risk marker for metabolic disorders. The strongest correlation was observed between uric acid and neck circumference,
suggesting this parameter may serve as a more sensitive anthropometric indicator than BMI or waist-to-hip rat
- Full text:2025120913304306167Өндгөвч уйланхайжих хам шинжтэй эмэгтэйчүүдийн бодисын солилцооны өөрчлөлт ба.pdf
