Association between hyperuricemia and risk of diabetes mellitus type 2: a prospective cohort study
- VernacularTitle:高尿酸血症与2型糖尿病风险的相关性研究：一项前瞻性队列研究
- Author:
Yijie HE
1
;
Jun ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Type 2 diabetes mellitus; Hyperuricemia; Correlation
- From: Journal of Public Health and Preventive Medicine 2025;36(6):72-75
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the correlation between hyperuricemia and the risk of type 2 diabetes mellitus, and to explore whether hyperuricemia is an independent risk factor of type 2 diabetes mellitus. Methods Using a prospective cohort study design, 300 adult volunteers who underwent physical examinations at the 3201 Hospital were recruited from January to December 2021. They were divided into a high uric acid group and a non-high uric acid group based on their uric acid levels. The incidence of diabetes in people with different uric acid levels was observed within two years through follow-up. SPSS26.0 software was used to statistically analyze the data. Results The data of this study showed that hyperuricemia significantly increased the risk of type 2 diabetes mellitus (P=0.01，OR=3.551). In addition, BMI had a significant impact on the risk of diabetes (P=0.000，OR =0.115), but the impact of age and gender was not statistically significant (both P>0.05). Conclusion Hyperuricemia is positively correlated to the incidence of type 2 diabetes. The higher the uric acid level, the higher the incidence of type 2 diabetes. The uric acid level has a good evaluation value in the incidence of type 2 diabetes mellitus. This finding provides a basis for early intervention of hyperuricemia as a potential risk factor for type 2 diabetes.
