Research progress on the clinical treatment methods and mechanisms of traditional Chinese medicine for pediatric allergic rhinitis
- VernacularTitle:中医药治疗儿童变应性鼻炎的临床治则治法及作用机制研究进展
- Author:
Zhongyuan ZHANG
1
;
Shuo ZENG
1
;
Zhenyao YANG
1
;
Keyan CHEN
1
;
Shaowei LIU
1
;
Shan ZHU
2
Author Information
1. Pediatric Medical College，Henan University of Chinese Medicine，Zhengzhou 450046，China
2. Dept. of Pediatrics，the Second Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450002，China
- Publication Type:Journal Article
- Keywords:
allergic rhinitis;
traditional Chinese medicine;
treatment by stages;
syndrome differentiation and treatment
- From:
China Pharmacy
2025;36(22):2879-2884
- CountryChina
- Language:Chinese
-
Abstract:
Allergic rhinitis （AR） is one of the most common chronic non-infectious inflammatory diseases in children. Traditional Chinese medicine （TCM） employs a comprehensive therapeutic system integrating treatment by stages and syndrome differentiation and treatment， demonstrating significant advantages in the management of pediatric AR. This article systematically reviews the clinical treatment methods and underlying mechanisms of TCM for pediatric AR in recent years. It is found that internal therapies （such as herbal formulas or Chinese patent medicines like Xiaoqinglong decoction， Yiqi tuomin decoction）， external therapies （including intradermal needles， acupoint application， tuina， and herbal nasal therapy）， as well as combined internal and external approaches （oral herbs combined with acupoint application）， have demonstrated significant effects in alleviating clinical symptoms， improving immune indicators， and reducing recurrence rates in children with AR. The underlying mechanisms are primarily associated with the regulation of signaling pathways such as Toll-like receptor/nuclear factor-kappa B and mitogen-activated protein kinase， thereby modulating immune balance， suppressing inflammatory responses， inhibiting pyroptosis， reducing mucus secretion， and promoting nasal mucosal repair.
