Clinical etiological analysis of bilateral middle cerebellar peduncle lesion
10.19845/j.cnki.zfysjjbzz.2025.0154
- VernacularTitle:双侧桥臂病变的临床病因学分析
- Author:
Juan WANG
1
;
Xing ZHANG
1
Author Information
1. Yellow River Sanmenxia Hospital Affiliated to Henan University of Science and Technology， Sanmenxia 472001， China
- Publication Type:Journal Article
- Keywords:
Middle cerebellar peduncles;
Clinical features;
Etiology
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(9):830-837
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and etiology of bilateral middle cerebellar peduncle lesion. Methods A retrospective analysis was performed for the clinical and imaging data of 59 patients who underwent cranial magnetic resonance imaging （MRI） in Central Hospital Affiliated to Dalian University of Technology and Yellow River Sanmenxia Hospital and were found to have abnormal signals of bilateral middle cerebellar peduncles， and a descriptive analysis was performed. Results As for clinical manifestations， among the 59 patients， there were 23 patients with unilateral limb weakness， 21 patients with dizziness， 12 patients with slurred speech， 8 patients with walking instability and limb numbness， 2 patients with drinking cough， dysphagia， double vision， and weakness of both lower limbs， 1 patient with limb tremor and bradykinesia， and 3 patients without symptoms. As for clinical diagnosis， among the 59 patients， there were 42 with Wallerian degeneration， 4 with acute cerebral infarction， 3 with demyelinating diseases of the central nervous system， 3 with hypertensive encephalopathy， 2 with multiple system atrophy， 1 with parkinsonism， 1 with the possibility of neuronal intranuclear inclusion disease， 1 with hypoparathyroidism and intracranial calcification， 1 with central nervous system lymphoma， and 1 with the possibility of ischemic or metabolic encephalopathy. Conclusion There are complex and diverse etiologies for bilateral middle cerebellar peduncle lesion， with Wallerian degeneration as the most common clinical diagnosis. Other diseases， such as acute cerebrovascular disease， inflammatory demyelinating diseases， neurodegenerative diseases， neoplastic diseases， and inherited metabolic diseases， can also be comorbid with bilateral middle cerebellar peduncle lesion.
