Expand screening, increase the diagnosis and treatment rates, and accelerate the elimination of the public health threat posed by hepatitis B
- Author:
ZHANG Shaoquan
;
LIN Bingliang
- Publication Type:Review
- Keywords:
Chronic hepatitis B;
screening;
diagnosis;
treatment;
public health
- From:
China Tropical Medicine
2025;25(3):259-
- CountryChina
- Language:Chinese
-
Abstract:
Chronic hepatitis B (CHB) caused by the hepatitis B virus (HBV), constitutes a significant public health issue, with approximately 254 million individuals affected globally, of which 75 million are in China. HBV infection not only severely impacts individual health, leading to conditions such as liver cirrhosis, hepatocellular carcinoma, and liver failure, but also imposes considerable economic burdens on society. This review provides an overview of the current epidemiological characteristics and disease burden of CHB, along with the progress towards, and challenges faced in achieving the World Health Organization's (WHO) goal of eliminating viral hepatitis as a public health threat by 2030. It delves into strategies aimed at reducing new infections, enhancing diagnosis rates, and improving treatment coverage. These strategies include universal screening, expanding the scope of antiviral therapy, and implementing specific measures for treating patients with end-stage liver disease. The review underscores critical actions necessary to accelerate the elimination of hepatitis B-related harms, proposing an integrated control and prevention strategy that incorporates new technologies and approaches. Achieving WHO's 2030 target requires concerted efforts from governments, healthcare institutions, and the broader community, alongside active public participation and support.
- Full text:2025111715091904781.Expand screening, increase the diagnosis and treatment rates, and accelerate the elimination of the public health threat posed by hepatitis B.pdf