Epidemiological investigation of one imported cholera epidemic in Shenzhen in 2024
- Author:
ZHANG Sheng
;
MA Ziqi
;
MA Zhifeng
- Publication Type:Case Reports
- Keywords:
Cholera;
imported epidemic;
epidemiological investigation;
Shenzhen
- From:
China Tropical Medicine
2025;25(2):253-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct an epidemiological investigation and analysis on one imported cholera case in Shenzhen in 2024, providing a reference for cholera prevention and control. Methods A cholera case and 86 close contacts in 2024 were investigated using methods of field epidemiological investigation. Real-time RT-PCR was employed for Vibrio cholerae nucleic acid detection and typing of collected specimens, followed by isolation culture, whole genome sequencing and analysis. Results One severe cholera case was confirmed in an Indian businessman, who recovered and was discharged after rescue and rehabilitation. The pathogen was identified as the toxigenic strain of Vibrio cholerae O1 serotype Ogawa, and genetic evolution analysis showed that it had a very close genetic relationship with Vibrio cholerae isolated from multiple countries such as Bangladesh and Pakistan. Among the 86 close contacts under medical observation, no abnormalities were found. A total of 75 close contact specimens and 38 environment smear specimens from epidemic sites were collected, all testing negative. Conclusion This is an imported cholera epidemic originating from India. The sensitivity of medical institutions to monitoring key infectious diseases such as cholera needs to be improved.
- Full text:202511171055155318322.Epidemiological investigation of one imported cholera epidemic in Shenzhen in 2024.pdf
