Investigation of infection control and prevention strategies on carbapenem-resistant Klebsiella pneumoniae nosocomial outbreak in a hospital in Shandong Province
- Author:
REN Yulian
;
CHEN Xiaoyan
;
JI Xiao
- Publication Type:Case Reports
- Keywords:
Nosocomial infection;
outbreak;
neurosurgical intensive care unit;
carbapenem-resistant Klebsiella pneumonia;
survey
- From:
China Tropical Medicine
2025;25(2):242-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and investigate a hospital-acquired outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP) in a hospital's neurosurgical intensive care unit (NSICU), and to implement rectification based on the investigation results, providing valuable insights and recommendations for controlling similar outbreaks caused by multi-drug-resistant strains. Methods The field epidemiological investigation was conducted to investigate five cases of clustered CRKP pulmonary infection in the NICU in Shandong in 2021. Hygienic monitoring of the environment was undertaken. The main occurrence stages were analyzed, effective control measures were taken, and the effectiveness of the control measures was evaluated. Results The study identified an outbreak of CRKP infections that occurred in the neurosurgical intensive care unit, with the beds of infection cases and spatial positions being centrally distributed. Hygienic monitoring was performed on environmental surfaces, as well as the hands and nasal cavities of medical and cleaning staff. In the first sampling, 3 samples from the patient bed units tested positive for CRKP, while no CRKP was detected on other surfaces, or in samples from the hands and nasal passages of the medical staff and air specimens. The CRKP strains found on surfaces had antibiotic resistance profiles consistent with the patient strains. No further related cases occurred after comprehensive control measures were implemented. Conclusions The comprehensive control measures, including enhanced ward disinfection and isolation, strict management of hand hygiene among medical staff, and personnel training, can effectively control the outbreak of CRKP hospital-acquired infections in NSICU.
- Full text:20251117105116929520.Investigation of infection control and prevention strategies on carbapenem-resistant Klebsiella pneumoniae nosocomial outbreak in a hospital in Shandong Province.pdf
