Re registration and influencing factors of newly diagnosed tuberculosis patients after successful treatment in Nantong, Jiangsu Province
- Author:
SUN Qing
;
WANG Xiaoping
;
FU Jian
- Publication Type:Journal Article
- Keywords:
Tuberculosis;
recurrence;
re registration
- From:
China Tropical Medicine
2024;24(12):1547-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and track the relapse of newly diagnosed tuberculosis patients in Nantong City, Jiangsu Province after successful treatment in tuberculosis, and to analyze the relapse of tuberculosis and its influencing factors, aiming to provide a reference for evaluating the long-term treatment effect of tuberculosis in Nantong and adjusting and improving tuberculosis prevention and control strategies. Methods Based on the Tuberculosis Management Information System, a subsystem of the Chinese Disease Prevention and Control Information System, the newly diagnosed active tuberculosis patients registered in Nantong in 2016 were taken as the observation queue, and the follow-up re registration of the included patients from 2016 to 2023 was searched through the system. Cox proportional hazard regression analysis was used to analyze the influencing factors of the recurrence of tuberculosis after successful treatment. Results In the subsequent observation of disease registration, 106 cases were re-registered for a second time with a re registration rate of 4.88%; 13 cases for a third time with a rate of 0.60%; and 2 cases for a fourth time with a rate of 0.09%. The overall annual re registration rate showed a downward trend, with the highest being 2.07% in 2017 and the lowest being 0.18% in 2022. Recurrences predominantly occurred among males, individuals over 40 years of age, farmers, and those with local registered residence personnel, and the recurrence rate of patients with positive etiology was higher than that of patients with negative etiology. Multivariate Cox regression analysis showed that male (HR=2.303, 95%CI:1.386-3.828), age≥40 (HR=2.144, 95%CI:1.157-3.973), farmer (HR=2.779, 95%CI:1.265-6.105), and positive sputum test at diagnosis (HR=2.837, 95%CI:1.932-4.164) were risk factors for recurrence in patients with pulmonary tuberculosis after successful treatment. Conclusions Tuberculosis prevention and control efforts should be strengthened by utilizing X-pert detection technology to diagnose tuberculosis and determine the outcome. Enhancements in the treatment management of newly diagnosed patients and regular follow-ups within two years after successful treatment are essential. Targeted prevention and control measures should be carried out for high-risk groups of tuberculosis recurrence.
- Full text:202511131532518302919.Re registration and influencing factors of newly diagnosed tuberculosis patients after successful treatment in Nantong, Jiangsu Province.pdf
