Histology of the fetal lungs at the different gestational age
- VernacularTitle:Жирэмсний янз бүрийн хугацааны ургийн уушигны гистологи
- Author:
Talalaev A G
1
;
Davidov I S
1
;
Oyungerel S
2
;
Tumenbayar B
2
;
Javzandulam E
2
;
Khulan B
2
;
Altantsetseg B
2
;
Mandakh-Erdene B
2
;
Nyamsuren P
2
;
Chimegsaikhan S
2
Author Information
1. Morozov Children’s City Clinical Hospital, Moscow, Russia; Peoples’ Friendship University of Russia named after Patrice Lumumba, Moscow, Russia
2. Mongolian National University of Medical Sciences
- Publication Type:Journal Article
- Keywords:
fetal lungs;
prealveolar structures;
pseudoglandular stage;
canalicular stage;
alveolar stage;
alveolar capillary membrane;
alveolocytes;
immunohistochemical study
- From:
Diagnosis
2025;115(4):11-16
- CountryMongolia
- Language:Mongolian
-
Abstract:
The study is devoted to the morphological characteristics of the maturation of lung tissue structures in the fetal period. Fetal histology of the lungs presents the intrauterine development of lung tissue in four successive stages: pseudoglandular, canalicular, saccular and alveolar, each has specific morphological criteria. The following morphological features are predetermined: the development of alveolar epithelium, the ratio of mesenchyme towards the area in alveolar spaces, the degree of proliferation and location of vessels of the microcirculatory bed towards prealveolar partitions. During the fetal period the alveolar columnar epithelium is flattened and differentiates into alveolocytes type I lung histology with the demonstration of histological preparations of the lungs at different stages of intrauterine development. Keywords: fetal lungs, prealveolar structures, pseudoglandular stage, canalicular stage, alveolar stage, alveolar capillary membrane, immunohistochemical study. 16 and II, the area of the mesenchyme gradually decreases and by the birth of a full-term newborn kid it is present mainly in the thickness between the alveolar septa, microcirculation vessels, initially laying deep in the thickness of the mesenchymal tissue, gradually proliferate, approach the pre-alveolar epithelium, channeling it with the formation of alveolar capillary membranes. Air exchange in the lung tissue is mainly provided with two factors: the presence of second-order alveolocytes capable of producing surfactant, and a sufficient formation of alveolias well. This work summarizes the basics of fetal lung histology with the demonstration of histological preparations of the lungs at different stages of intrauterine development.
- Full text:2025111115462354772Diagnosis-2025-115(4)-11-16.pdf
