Follow-up Analysis of 267 Cases of Extracardiac Conduit Total Cavopulmonary Connection in a Single Center
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2025.0518
- VernacularTitle:单中心267例心外管道全腔肺动脉连接手术的随访分析
- Author:
Fangqiong QIN
1
;
Shusheng WEN
2
;
Jimei CHEN
2
;
Xiaoxia CHEN
1
Author Information
1. Department of Operation Room of Cardiac Surgery， Guangdong Cardiovascular Institute // Guangdong Academy of Medical Sciences // Guangdong Provincial People’s Hospital， Southern Medical University， Guangzhou 510080， China
2. Department of Cardiac Surgery， Guangdong Cardiovascular Institute // Guangdong Academy of Medical Sciences // Guangdong Provincial People’s Hospital， Southern Medical University， Guangzhou 510080， China
- Publication Type:Journal Article
- Keywords:
single ventricle;
total cavopulmonary connection;
extracardiac conduit;
fatality;
influence factors
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2025;46(5):881-888
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the outcomes and surgical experiences of 267 cases of extracardiac conduit total cavopulmonary connection （TCPC） in patients with functional single ventricles. MethodsClinical data were collected from 267 patients who underwent extracardiac conduit TCPC at Guangdong Provincial People's Hospital from October 2004 to August 2021. Among them， 185 were male （69.3%） and 82 were female （30.7%）. The age was 5.71 （4.08-10.90） year， and the weight was 17.5 （14.5-26.2） kg. A median sternotomy approach was used， and the surgery was completed under cardiopulmonary bypass. The preoperative， intraoperative and postoperative follow-up data of the patients were collected， and the survival prognosis and its influencing factors were analyzed. ResultsThe operative time was 330.0 （267.5-405.0） min， the cardiopulmonary bypass time was 124.0 （96.0-163.0） min， and the aortic cross-clamp time was 48.0 （0.0-81.0） min. The duration of mechanical ventilation after surgery was 8.7 （5.0-19.1） h， and the hospital stay was 34.0 （28.0-49.0） d. The follow-up period was 8.0 （4.6-11.0） year， with 8 early deaths （3.0%）， 20 late deaths （7.5%）. The independent risk factors of fatality in patients after extracardiac conduit TCPC included male， heterotaxy syndrome， preoperative pulmonary artery pressure， intraoperative blood loss， the duration of mechanical ventilation， and the 48 h average vasoactive-inotropic score. ConclusionsThe extracardiac conduit TCPC is quite effective in treating patients with functional single ventricle. The early postoperative fatality is low， while the late fatality is relatively high. Therefore， it is necessary to pay close attention to the long-term survival situation of this group of patients. The analysis of risk factors emphasizes the importance of perioperative refined assessment and individualized treatment. It may help further improve the therapeutic outcomes of such surgeries， including selecting appropriate patients， performing careful operations， ensuring meticulous hemostasis， and shortening the duration of postoperative mechanical ventilation.
