Safe platelet threshold in patients undergoing endoscopic variceal ligation and cyanoacrylate injection due to esophagogastric variceal bleeding： Consensus and challenges

Luyao JIA; Yuqiang NIE; Biao XIE; Hongbo GAO; Chuo LI; Chunming HUANG

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Safe platelet threshold in patients undergoing endoscopic variceal ligation and cyanoacrylate injection due to esophagogastric variceal bleeding： Consensus and challenges

VernacularTitle:食管胃静脉曲张破裂出血行内镜下曲张静脉套扎术和内镜下组织胶注射术的血小板安全阈值：共识与挑战
Author: Luyao JIA ¹ ; Yuqiang NIE ² ; Biao XIE ¹ ; Hongbo GAO ³ ; Chuo LI ⁴ ; Chunming HUANG ¹
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1. Department of Gastroenterology Guangzhou Eighth People’s Hospital， Guangzhou Medical University Guangzhou 510440 China
2. Department of Gastroenterology， Guangzhou First People’s Hospital， Guangzhou 510180， China
3. Department of Severe Liver Disease Guangzhou Eighth People’sHospital， Guangzhou Medical University Guangzhou 510440 China
4. Department of Neurology， Guangzhou Eighth People’s Hospital， Guangzhou Medical University Guangzhou 510440 China
Publication Type:Review
Keywords: Esophageal and Gastric Varices; Cuff Ligating Therapy; Chemoembolization， Therapeutic; Platelet Count
From: Journal of Clinical Hepatology 2025;41(9):1908-1912
CountryChina
Language:Chinese
Abstract: Esophagogastric variceal bleeding is a common complication and the leading cause of death in advanced liver cirrhosis， and endoscopic variceal ligation （EVL） and endoscopic cyanoacrylate injection （ECI） are commonly used treatment strategies. Thrombocytopenia is one of the most common hematological complications in liver cirrhosis， and patients with severe thrombocytopenia have the potential risk of bleeding， which may affect treatment decision-making by clinicians and endoscopists. This article reviews the evolution of guidelines and clinical research advances regarding EVL/ECI in China and globally， in order to provide a basis for decision making among clinicians.