The role of dendritic cells in autoimmune liver diseases and autoimmune pancreatitis
- VernacularTitle:树突状细胞在自身免疫性肝病和自身免疫性胰腺炎中的作用
- Author:
Wenfeng XI
1
;
Xiaoyin BAI
1
;
Aiming YANG
1
Author Information
- Publication Type:Review
- Keywords: Autoimmune Diseases; Dendritic Cells; Immune Tolerance
- From: Journal of Clinical Hepatology 2025;41(9):1902-1907
- CountryChina
- Language:Chinese
- Abstract: Dendritic cells （DCs）， as key regulatory cells in the immune system， play a significant role in the pathogenesis of autoimmune diseases. This article reviews the mechanism of action of DCs and related research advances in autoimmune liver diseases （including autoimmune hepatitis， primary biliary cholangitis， and primary sclerosing cholangitis） and autoimmune pancreatitis. By summarizing the functions and heterogeneity of DCs in these diseases， this article reveals the crucial role of DCs in the imbalance of immune tolerance and chronic inflammation. Related research findings provide an important basis for a deep understanding of the role of DCs in autoimmune liver diseases and autoimmune pancreatitis and lay a foundation for the development of precise treatment strategies.
