Application of Lycii Fructus and Its Compound Formulas in Central Nervous System Diseases： A Review
10.13422/j.cnki.syfjx.20250639
- VernacularTitle:枸杞子及其复方在中枢神经系统疾病中的应用研究进展
- Author:
Ruyang CHENG
1
;
Weining SONG
1
;
Xin JIANG
1
;
Yehao WANG
1
;
Chi ZHANG
1
;
Zhendong ZHANG
1
;
Shumin LIU
2
Author Information
1. Graduate School， Heilongjiang University of Chinese Medicine， Harbin 150040， China
2. Research Institute of Chinese Medicine， Heilongjiang University of Chinese Medicine， Harbin 150040， China
- Publication Type:Journal Article
- Keywords:
Lycii Fructus;
Lycii Fructus polysaccharide;
compound formulas;
neurodegenerative diseases;
central nervous system
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(22):273-281
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of central nervous system （CNS） diseases is complex， seriously affecting patients' physical and mental health and imposing a heavy economic burden on society. Western medicine shows limited efficacy in treating CNS diseases and is often associated with numerous adverse reactions and contraindications. Chinese medicine Lycii Fructus exhibits multiple pharmacological effects， including immune regulation， enhancement of hematopoietic function， liver protection， anti-tumor， hypoglycemic， antipyretic， anti-aging， and anti-radiation activities， and has gradually been applied in clinical treatment. In recent years， the active components of Lycii Fructus have attracted considerable attention for their potential therapeutic effects on CNS diseases. Studies indicate that these active components may exert neuroprotective effects through anti-inflammatory and antioxidant actions， inhibition of neuronal apoptosis， and repair of neuronal damage， involving multiple targets and pathways. This review summarizes the therapeutic effects of Lycii Fructus active components in CNS diseases over the past decade by searching PubMed， CNKI， Wanfang Data， and other electronic databases， aiming to provide new treatment strategies and insights for future research on Lycii Fructus in CNS disorders.
