Precision infusion of cryoprecipitate in rare bleeding disorders
10.13303/j.cjbt.issn.1004-549x.2025.09.004
- VernacularTitle:冷沉淀在罕见出血性疾病中的精准输注
- Author:
Changkui SUN
1
;
Tiantian WANG
1
;
Jie WANG
1
;
Yunhai FANG
1
Author Information
1. Shandong Blood Center, Jinan 250014, China
- Publication Type:Journal Article
- Keywords:
cryoprecipitate;
precise infusion;
coagulation factor Ⅷ;
fibrinogen;
von Willebrand factor;
coagulation factor ⅩⅢ
- From:
Chinese Journal of Blood Transfusion
2025;38(9):1150-1153
- CountryChina
- Language:Chinese
-
Abstract:
The coagulation factors in cryoprecipitate are mainly coagulation factor Ⅷ, fibrinogen, von Willebrand factor (VWF), and coagulation factor ⅩⅢ. This article provides different treatment dosages and plans for different patients with rare coagulation disorders based on their actual conditions referring to international and domestic guidelines and consensus. In order to achieve precise infusion for cryoprecipitate, it is necessary to avoid poor treatment effects caused by insufficient doses, as well as waste of blood components and the risk of thrombosis caused by excessive infusion.