Relationship between geriatric nutritional risk index and osteoporosis in elderly hypertensive population
10.3969/j.issn.1006-2483.2025.05.038
- VernacularTitle:老年人营养风险指数与老年高血压人群骨质疏松症的关系
- Author:
Kaishunzi LIU
1
;
Min DOU
1
;
Jinhua DUAN
1
;
Qian WANG
1
Author Information
1. Department of Health Management , the Second Affiliated Hospital of Xi'an Jiaotong University , Xi'an , Shaanxi 710015 , China
- Publication Type:Journal Article
- Keywords:
Geriatric nutritional risk index;
Elderly hypertensive population;
Osteoporosis;
Logistic regression analysis
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between geriatric nutritional risk index (GNRI) and osteoporosis (OP) in elderly hypertensive population. Methods Elderly physical examination population who received dual-energy bone mineral density examination and bone metabolic marker test in the hospital were selected from January 2021 to December 2024. According to whether they had hypertension and dual-energy bone mineral density results, the enrolled patients were divided into hypertension OP group (142 cases ), hypertension non-OP group (173 cases), non-hypertension OP group (102 cases) and non-hypertension non-OP group (100 cases). GNRI of all study subjects was measured. The correlation of GNRI and the occurrence of OP was explored by logistic regression analysis. The predictive efficiency of GNRI on the occurrence of OP was evaluated by receiver operating characteristic (ROC) curve. Results The BMD and GNRI in the hypertension group, and the non-hypertension OP group were significantly lower than those in the non-hypertension non-OP group (P<0.05). Compared with the hypertension non-OP group, the BMI, GNRI, BMD, and 25-OH Vit D in the hypertension OP group were significantly reduced (P<0.05) while the PTH level was significantly enhanced (P<0.05).logistic regression analysis showed that GNRI, 25-OH Vit D and PTH were closely related to OP in the elderly hypertensive population (P < 0.05). ROC curve analysis manifested that the AUC value of GNRI alone in predicting OP in elderly hypertensive population was 0.802, which was higher than that of 25-OH Vit D (AUC=0.723) and PTH (AUC=0.643). The AUC, sensitivity and specificity of combination of GNRI, 25-OH Vit D and PTH in predicting OP in elderly hypertensive population were 0.837, 66.20% and 86.13% (P<0.05). Conclusion GNRI is closely related to the occurrence of OP in elderly hypertensive population, and GNRI can be used as a potential indicator to assess the risk of OP.
