Risk factors for cough variant asthma and its relationship with changes in indoor environment
10.3969/j.issn.1006-2483.2025.05.032
- VernacularTitle:咳嗽变异性哮喘与室内环境变化的危险因素分析
- Author:
Jieyu SHI
1
;
Dan ZHOU
1
;
Mengtan LIU
1
Author Information
1. Department of Respiratory and Critical Care Medicine , the First Affiliated Hospital of Naval Military Medical University (Shanghai Changhai Hospital) , Shanghai 200082 , China
- Publication Type:Journal Article
- Keywords:
Cough variant asthma;
Indoor environment;
Risk factor
- From:
Journal of Public Health and Preventive Medicine
2025;36(5):145-148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for cough variant asthma (CVA) and investigate the influence of indoor environment on CVA. Methods From July 2021 to August 2024, 315 patients admitted to the hospital due to CVA were selected as the CAV group. Meanwhile, 100 healthy individuals were selected as the control group. Clinical data of all subjects were collected. Univariate analysis and multivariate logistic regression analysis were used to identify the influencing factors of CVA. Results The proportions of subjects with family history and recurrent respiratory tract infection in the CVA group were higher than those in the control group (P<0.05). The CVA group had significantly higher rates of indoor renovation, mold growth, infrequent bedding cleaning, opening window for ventilation once to 3 times a week, keeping pets, and passive smoking compared to the control group within one year, and the differences were statistically significant (P<0.05). Multivariate logistic regression analysis results showed that indoor-decoration in the past year (OR=2.282, 95%CI: 1.1454.549), mould growth (OR=2.036, 95%CI: 1.228-3.376), opening window for ventilation once to 3 times a week (OR=1.895, 95%CI: 1.253-2.865), seldom cleaning bedding (OR=2.257, 95%CI: 1.132-4.499), keeping pets (OR=2.071, 95%CI: 1.146-3.743), and passive smoking (OR=2.208, 95%CI: 1.377-3.541) were independent risk factors for CVA (P<0.05). Conclusion There is a significant correlation between the occurrence of CVA and indoor environment. Changes in indoor environment include indoor-decoration in the past year, mould growth, low frequency of opening window for ventilation, low frequency of bedding cleaning, keeping pets and passive smoking which are risk factors for the occurrence of CVA.
