Clinical Characteristics and TCM Syndrome Patterns in 721 Female Patients with Pulmonary Nodules
10.3971/j.issn.1000-8578.2025.25.0159
- VernacularTitle:721例女性肺结节患者临床特征及中医证素和证候分布
- Author:
Yue LUO
1
;
Yue LI
2
;
Jiaqi HU
2
;
Huibo YU
1
;
Linfeng WANG
2
;
Baojin HUA
2
;
Rui LIU
2
Author Information
1. Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China;Oncology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
2. Oncology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
- Publication Type:CLINICALRESEARCH
- Keywords:
Pulmonary nodules;
Female;
Clinical features;
Syndrome element;
Syndrome
- From:
Cancer Research on Prevention and Treatment
2025;52(9):747-757
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical information of female patients with pulmonary nodules and the distribution of traditional Chinese medicine (TCM) syndromes and their elements. Methods A cross-sectional study was conducted to collect the basic information, medical history data, image data, and four diagnostic information of female patients with pulmonary nodules. The distribution characteristics of TCM syndromes and their elements in female patients with pulmonary nodules were determined by KMO test, Bartlett spherical test, systematic cluster analysis, chi-square test, and other methods. Results A total of 721 female patients with pulmonary nodules were included in this study. The patients were mainly 45-59 years old, had secondary school education or above, and had a history of oil smoke exposure as clinical characteristics. The pulmonary nodules were mainly 6-10 mm in size and appeared as multiple and ground glass nodules. The clinical symptoms were mainly fatigue, emotional irritability, and shortness of breath. The main syndromes of disease location were the spleen, liver, and lung; and the main syndromes of disease were phlegm, dampness, and qi deficiency. The main complex syndromes were spleen deficiency and dampness, liver stagnation, and qi/yin deficiency. Conclusion Middle age, high education, and multiple small ground glass nodules are the clinical characteristics of female patients with pulmonary nodules. Exposure to oil smoke is an important cause of the occurrence of female pulmonary nodules. During treatment, attention should be paid to strengthening the spleen, removing dampness, soothing the liver, regulating and tonifying qi, and nourishing yin.
