Progress and prospects in regenerative medicine in ophthalmology
10.3980/j.issn.1672-5123.2025.10.01
- VernacularTitle:眼科再生医学的进展与前景
- Author:
Yannian HUI
1
Author Information
1. Eye Institute of PLA;Department of Ophthalmology, Xijing Hospital, Air Force Medical University, Xi'an 710032, Shaanxi Province, China
- Publication Type:Journal Article
- Keywords:
ophthalmology;
regenerative medicine;
stem cells;
gene editing;
biomaterials;
bioengineering
- From:
International Eye Science
2025;25(10):1547-1550
- CountryChina
- Language:Chinese
-
Abstract:
Regenerative medicine(RM)is an emerging interdisciplinary field that integrates molecular and cellular biology, gene editing, biomaterials and bioengineering to activate one's own potential, replace, repair or regenerate damaged tissues and organs. Ophthalmology is one of the most active and promising fields in RM, and is highly valued by governments and research institutions around the world. Its progress represents the most cutting-edge aspects of medical and ophthalmic research. Currently, the treatment targets of ophthalmic RM include ocular surface and corneal diseases, retinal diseases such as diabetic retinopathy, age-related macular degeneration, inherited retinal diseases, glaucoma and other irreversible ophthalmic disorders. Some preclinical or clinical trials have shown encouraging results. The challenges for RM include ethics, cell delivery, long-term efficacy and safety, etc. We herein briefly introduce the relevant concepts, research status and progress, and look forward to continuous new achievements in domestic RM.
