A case of postoperative candida bloodstream infection in patients with digestive tract perforation
10.12206/j.issn.2097-2024.202312012
- VernacularTitle:消化道穿孔患者术后继发念珠菌血流感染的病例分析
- Author:
Guangwei FENG
1
;
Jing ZHANG
2
;
Yangxi LIU
3
;
Min CUI
3
Author Information
1. Department of Pharmacy, Tianlin Community Health Service Center of Xuhui District, Shanghai 200233, China.
2. Department of Pharmacy, Dahua Hospital of Xuhui District, Shanghai 200237, China.
3. Department of Pharmacy, Renji Hospital affiliated to School of Medicine of Shanghai Jiaotong University, Shanghai 200127, China.
- Publication Type:Medicine&Clinical
- Keywords:
caspofungin;
Candida infection;
fluconazole
- From:
Journal of Pharmaceutical Practice and Service
2025;43(9):463-465
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the drug selection, usage, dosage and effect of clinical pharmacists in the treatment of secondary Candida bloodstream infection in patients with digestive tract perforation, and provide reference for rational clinical use of such anti-infection therapy. Methods During the treatment of Candida infection, anti-infection specialist clinical pharmacists suggested replacing fluconazole for anti-infection treatment, and adjusted the usage and dosage of caspofungin to ensure the application of full treatment course. Results The patient’s Candida bloodstream infection was effectively controlled. Conclusion Echininocandins such as caspofungin are the first choice for Candida infection. The maintenance dose should be reduced to 35 mg qd in patient with moderate liver function injury, and the anti-infection treatment should be done at least 14 days after the blood culture being negative. Clinical pharmacists participate in clinical pharmaceutical care practices such as clinical ward rounds, and actively assist doctors to develop individualized anti-infection programs, which could improve the level of clinical drug use and the clinical outcome of diseases.
