Research progress on predicting the growth of pulmonary nodules based on CT imaging
- VernacularTitle:基于CT 影像预测肺结节生长规律的研究进展
- Author:
Wenhe XUE
1
,
2
;
Nan CHEN
1
;
Lunxu LIU
1
Author Information
1. Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
2. West China School of Medicine, Sichuan University, Chengdu, 610041, P. R. China
- Publication Type:Journal Article
- Keywords:
Pulmonary nodules;
CT imaging;
growth prediction;
radiomics;
deep learning;
personalized treatment
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(05):581-586
- CountryChina
- Language:Chinese
-
Abstract:
The widespread application of low-dose computed tomography (LDCT) has significantly increased the detection of pulmonary small nodules, while accurate prediction of their growth patterns is crucial to avoid overdiagnosis or underdiagnosis. This article reviews recent research advances in predicting pulmonary nodule growth based on CT imaging, with a focus on summarizing key factors influencing nodule growth, such as baseline morphological parameters, dynamic indicators, and clinical characteristics, traditional prediction models (exponential and Gompertzian models), and the applications and limitations of radiomics-based and deep learning models. Although existing studies have achieved certain progress in predicting nodule growth, challenges such as small sample sizes and lack of external validation persist. Future research should prioritize the development of personalized and visualized prediction models integrated with larger-scale datasets to enhance predictive accuracy and clinical applicability.