Research Progress on Relationship Between EBV and HPV Coinfection and Related Malignant Tumors
10.3971/j.issn.1000-8578.2025.25.0066
- VernacularTitle:EBV与HPV合并感染与相关恶性肿瘤的关系研究进展
- Author:
Yang LIN
1
;
Ke GU
1
Author Information
1. Department of Radiotherapy, Jiangnan University Affiliated Hospital, Wuxi 214122, China;Wuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
- Publication Type:REVIEWS
- Keywords:
Epstein-Barr virus;
HPV;
Cervical neoplasms;
Oral cavity neoplasms;
Nasopharyngeal neoplasms;
Coinfection
- From:
Cancer Research on Prevention and Treatment
2025;52(8):711-716
- CountryChina
- Language:Chinese
-
Abstract:
Epstein-Barr virus (EBV) and human papillomavirus (HPV) play an important role in the occurrence and development of various malignant neoplasms, such as cervical neoplasms, oral cavity neoplasms, and nasopharyngeal neoplasms. This review primarily discusses the co-infection of EBV and HPV in cervical neoplasms, oral cavity neoplasms, and nasopharyngeal neoplasms. Many in-depth discussions have focused on the role of EBV and HPV co-infection in related neoplasms. Most studies believed that they are complementary to each other, but a few argued that the infection between these two viruses is mutually exclusive. Clarifying the mechanisms and roles of EBV and HPV co-infection in cervical neoplasms, oral cavity neoplasms, and nasopharyngeal neoplasms will provide important breakthroughs for the treatment and prevention of virus-related neoplasms.
