Research progress on the correlation between gut microbiota dysbiosis and obesity
10.3969/j.issn.1006-2483.2025.04.029
- VernacularTitle:肠道菌群失调与肥胖关系的相关性研究进展
- Author:
Li HUANG
1
;
Jiahui YANG
1
Author Information
1. General Practice Medical Center , West China Hospital , Sichuan University / West China School of Nursing , Sichuan University , Chengdu , Sichuan 610041 , China
- Publication Type:Journal Article
- Keywords:
Obesity;
Gut Microbiota Dysbiosis;
Research Progress
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):128-132
- CountryChina
- Language:Chinese
-
Abstract:
Obesity is a significant global health issue, with rising incidence influenced by genetics and environment. Recent studies link obesity to the gut microbiota, suggesting a crucial interaction between our microbiome and this condition. Managing gut microbiota is emerging as a novel approach to treating obesity, yet the intricate relationships among genetics, environment, and microbiota in obesity are not fully deciphered. This review aims to highlight gut microbiota characteristics in obesity and its mechanisms, offering insights for targeted interventions. It discusses the influence of genetic and environmental factors on microbiota and obesity. Additionally, it underscores the potential of modifying gut microbiota as a therapeutic strategy, considering its challenges and prospects. The review concludes with future research directions, advocating integrated approaches combining genetic, microbial, and environmental factors for effective obesity management.
