Clinical characteristics and influencing factors of chronic obstructive pulmonary disease patients complicated with heart failure in Nanjing
10.3969/j.issn.1006-2483.2025.04.014
- VernacularTitle:南京地区慢性阻塞性肺疾病患者合并心力衰竭的临床特征及影响因素
- Author:
Yumin ZHU
1
;
Guoxin ZHANG
2
;
Liping YIN
3
;
Fan CHEN
4
;
Bowen HUANG
1
;
Qian LI
1
Author Information
1. Department of Respiratory Medicine , Nanjing Combined Hospital of Traditional Chinese and Western Medicine , Nanjing , Jiangsu 210000 , China
2. Department of Geriatrics , Qixia District Hospital , Nanjing , Jiangsu 210046 , China
3. Department of Geriatrics , Lishui District People's Hospital , Nanjing , Jiangsu 211200 , China
4. Department of Respiratory Medicine , Pukou Hospital of Traditional Chinese Medicine , Nanjing , Jiangsu 211800 , China
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Heart failure;
Clinical features
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):64-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features of chronic obstructive pulmonary disease (COPD) patients with heart failure (HF) in Nanjing and explore the influencing factors. Methods A total of 773 COPD inpatients were selected from January 2021 to January 2024 in Nanjing Combined Hospital of Traditional Chinese and Western Medicine, Nanjing Qixia District Hospital, Nanjing Lishui District People's Hospital, Nanjing Pukou District Hospital of Traditional Chinese Medicine and Nanjing First Hospital., and were divided into 2 groups according to the presence or absence of combined HF. The general data and medical records of the two groups were compared, the clinical characteristics of COPD patients with HF were summarized, and the influencing factors of COPD patients with HF were analyzed by multivariate logistic regression. Results Among the 242 patients (31.31%) with COPD had HF, chronic paroxysmal dyspnea was the most common first symptom, 169 patients (69.83%) had left heart failure, 63 patients (30.17%) were diagnosed as right heart failure or global heart failure , 17 patients (7.02%) had myocardial infarction. Multivariate logistic regression analysis showed that the risk of HF was 1.678 times and 1.691times higher in COPD groups ≥ 50 years old and male COPD groups than in < 50 years old and female groups, respectively; the risk of HF was 1.491 times higher in COPD groups engaged in physical work than in physical work groups; the risk of HF was 1.447 times and 1.580 times higher in COPD groups with hypertension and coronary heart disease than in COPD groups without hypertension and coronary heart disease, respectively; the risk of HF was 1.859 times higher in COPD groups smoking>400 vial/year than in COPD groups≤400 vial/ year; the risk of HF was 1.757 times higher in COPD groups with acute exacerbation frequency≥2 times/year than in COPD groups<2 times/year; the above differences were statistically significant (P<0.05). Conclusion Attention should be paid to elderly, male and heavy physical work group of COPD patients. Active treatment of hypertension and coronary heart disease, effective tobacco control and reduction of the frequency of acute exacerbation are effective ways to reduce the risk of HF in COPD patients in Nanjing.
