Sleep status in patients with Parkinson's disease and its relationship with dyskinesia and negative emotions
10.3969/j.issn.1006-2483.2025.04.011
- VernacularTitle:帕金森患者睡眠现状及其与运动障碍不良情绪的关系
- Author:
Min WU
1
;
Liang ZHONG
1
;
Heng LIN
1
;
Xi YANG
1
Author Information
1. Department of Neurology , The Third People's Hospital of Chengdu , Chengdu , Sichuan 610031 , China
- Publication Type:Journal Article
- Keywords:
Parkinson' disease;
Sleep;
Dyskinesia;
Negative emotions;
Correlation
- From:
Journal of Public Health and Preventive Medicine
2025;36(4):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the sleep status in patients with Parkinson's disease (PD), and to explore its relationship with dyskinesia and negative emotions. Methods A total of 308 patients with PD who met the inclusion and exclusion criteria in the hospital from September 2022 to May 2024 were selected as the research subjects. The scores of sleep status [Pittsburgh Sleep Quality Index (PSQI)], dyskinesia [Simplified Fugl-Meyer Motor Assessment (FMA)] and negative emotions [Beck Anxiety Inventory (BAI), Beck Depression Inventory-II (BDI-II)] were analyzed, and the PSQI score was compared among patients with different demographic characteristics. Pearson correlation analysis was performed to analyze the correlation of sleep with dyskinesia and negative emotions in patients with PD. Results The total score of PSQI scale was (6.16±0.97) points in 308 PD patients, of which 208 cases (67.53%) were complicated with sleep disorders. The proportions of female, 61-75 years old, technical secondary school or below, disease course of 4 years and above, Hoehn-Yahr stage IV and unmarried status in the sleep disorder group were higher than those in the non-sleep disorder group (P<0.05). Compared with the non-sleep disorder group, the FMA score in the sleep disorder group was lower (P<0.05) while the BAI score and BDI-II score were higher (P<0.05). Pearson correlation analysis revealed that PSQI was negatively correlated with FMA (r=-0.489, P<0.05), and was positively correlated with BAI and BDI-II (r=0.476, 0.502, P<0.05). Conclusion The incidence rate of sleep disorders in PD patients is high. PSQI is negatively correlated with FMA, and is positively correlated with BAI and BDI-II.
