Wernekinck commissure syndrome caused by ischemic stroke
10.19845/j.cnki.zfysjjbzz.2025.0050
- VernacularTitle:缺血性脑卒中所致Wernekinck连合综合征
- Author:
Cuilin PENG
1
;
Zhihua ZHOU
2
Author Information
1. 广东药科大学附属第一医院神经内科，广东 广州 510080
2. 广东药科大学附属第一医院神经内科，广东 广州 510080;广东药科大学附属第一医院中西医结合神经病学研究所，广东 广州 510080
- Publication Type:Journal Article
- Keywords:
Wernekinck commissure syndrome;
Wernekinck commissure;
Decussation of superior cerebellar peduncle;
Palatal myoclonus;
Hypertrophy of the inferior olivary nucleus
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(3):249-254
- CountryChina
- Language:Chamorro
-
Abstract:
Objective Wernekinck commissure syndrome（WCS）is a rare syndrome in clinical practice caused by Wernekinck commissure lesions， with the clinical manifestations of bilateral limb ataxia and dysarthria. This article analyzes the clinical features and other characteristics of WCS caused by ischemic stroke through a literature review， in order to improve the understanding of this syndrome among clinicians. Methods CNKI， Wanfang Data， and PubMed databases were searched for articles on WCS caused by ischemic stroke， and the clinical manifestations of reported WCS cases were analyzed and summarized. Results Among the 57 patients with WCS caused by ischemic stroke，48（84.2%） had bilateral cerebellar ataxia，48（84.2%） had dysarthria， 36（63.2%） had varying degrees of limitation of eye movement， 36 （63.2%）had dizziness，30（52.6%）had nystagmus，12（21.1%） had disturbance of consciousness，9（15.8%）had Holmes tremor， and 7（12.3%）had palatal myoclonus. When lesions involved Wernekinck commissure and the adjacent structures， patients might have the manifestations such as bilateral ataxia， dysarthria， limitation of eye movement， nystagmus， Holmes tremor， and disturbance of consciousness. Conclusion WCS caused by ischemic stroke has the main manifestations of bilateral limb ataxia， dysarthria，and eye movement disorder， and palatal myoclonus is relatively rare in the early stage and usually occurs along with hypertrophy of the inferior olivary nucleus in the late stage.
- Full text:202507161006107882缺血性脑卒中所致Wernekinck连合综合征.pdf
