Hypertrophic spinal pachymeningitis associated with myeloperoxidase antibody and anti‑neutrophil cytoplasmic antibody：A case report and literature review
10.19845/j.cnki.zfysjjbzz.2025.0012
- VernacularTitle:MPO-ANCA相关肥厚性硬脊膜炎1例报告并文献复习
- Author:
Chunxia ZHAO
1
;
Peng XU
2
Author Information
1. 济宁医学院，山东 济宁 272002
2. 济宁医学院附属医院神经内科，山东 济宁 272000
- Publication Type:Journal Article
- Keywords:
Anti‑neutrophil cytoplasmic antibody;
Myeloperoxidase;
Hypertrophic spinal pachymeningitis;
Hypertrophic pachymeningitis;
Imaging
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(1):56-59
- CountryChina
- Language:Chinese
-
Abstract:
Anti-neutrophil cytoplasmic antibody-associated small-vessel vasculitis（ANCA-AAV） is an autoimmune disease that can involve multiple systems throughout the body， and approximately 15% of patients with AAV have central nervous system involvement. Hypertrophic spinal pachymeningitis （HSP） is a rare clinical form with nervous system involvement characterized by thickening of the dura mater， inflammatory response，and fibrosis. This article reports a case of HSP associated with myeloperoxidase antibody and ANCA and summarizes its clinical features and imaging characteristics with reference to the latest literature，so as to enhance the understanding of HSP among clinicians and reduce missed diagnosis or misdiagnosis.
- Full text:2025071510404021489MPO-ANCA相关肥厚性硬脊膜炎1例报告并文献复习.pdf
